Sökning: "insertion sequence"

Visar resultat 1 - 5 av 80 avhandlingar innehållade orden insertion sequence.

1. 1. Lithium-ion insertion in a V6O13 cathode

   Författare :Örjan Bergström; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; cathode material; vanadium oxide; lithium insertion; in situ X-ray diffraction; deformation electron density refinement; Kemi; Chemistry; Kemi; Inorganic Chemistry; oorganisk kemi;

   Sammanfattning : The transition metal oxide V6O13 is a promising cathode material for high-capacity lithium-polymer batteries in conjunction with a lithium-metal anode. The electro-chemical behaviour of V6O13 has its origin in the ability of the vanadium ions to change their-oxidation states, combined with the open nature of its crystal structure which allows lithium ions to diffuse through it. LÄS MER

3. 2. Integration and topology of membrane proteins

   Författare :Carolina Boekel; Gunnar von Heijne; IngMarie Nilsson; Stephen High; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; insertion; Sec61; translocation; Biochemistry; Biokemi; biokemi; Biochemistry;

   Sammanfattning : Membrane proteins comprise around 20-30% of most proteomes. They play important roles in most biochemical pathways. All receptors and ion channels are membrane proteins, which make them attractive targets for drug design. Membrane proteins insert and fold co-translationally into the endoplasmic reticular membrane of eukaryotic cells. LÄS MER

4. 3. Sequence-based predictions of membrane-protein topology, homology and insertion

   Författare :Andreas Bernsel; Gunnar von Heijne; Volkhard Helms; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; membrane protein; topology prediction; hidden markov model; homology detection; Sec translocon; Bioinformatics; Bioinformatik; Biochemistry; biokemi;

   Sammanfattning : Membrane proteins comprise around 20-30% of a typical proteome and play crucial roles in a wide variety of biochemical pathways. Apart from their general biological significance, membrane proteins are of particular interest to the pharmaceutical industry, being targets for more than half of all available drugs. LÄS MER

5. 4. Studies on cell wall-attached proteins of Streptococcus pyogenes

   Författare :Magnus Rasmussen; Infektionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insertion sequence; phase variation; collagen-like; alpha2-macroglobulin; pattern; virulence; surface protein; Stretococcus pyogenes; cell wall-attached protein; Clinical biology; Klinisk biologi;

   Sammanfattning : Cell wall-attached proteins (CWPs) are important for the virulence of Gram-positive bacteria, but are also targets for the host immune system. CWPs have a conserved COOH-terminal region, responsible for cell wall-sorting. A pattern based on this conserved region was developed. LÄS MER

7. 5. Antibody Evolution and Repertoire Development

   Författare :Johan Lantto; Institutionen för immunteknologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; serology; transplantation; Immunologi; serologi; virus neutralization; trinucleotide repeat; insertion; immunoglobulin variable genes; human cytomegalovirus; glycoprotein B; deletion; antibody; antibody repertoire;

   Sammanfattning : Antibodies are key players of the immune system in higher vertebrates, which provide a defense against potentially lethal threats from the environment. Besides their importance in the immune defense, antibodies have a great potential as reagents in biological chemistry and diagnostics, and as therapeutic agents against both infectious diseases and cancer. LÄS MER