Sökning: "infected erythrocytes"

Visar resultat 1 - 5 av 24 avhandlingar innehållade orden infected erythrocytes.

  1. 1. Host cell adhesion of Plasmodium falciparum-infected erythrocytes

    Författare :Carl Johan Treutiger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Plasmodium falciparum; erythrocyte rosetting; cytoadherence; cerebral malaria; PfEMPI; serum proteins; PECAM-I CD31;

    Sammanfattning : Excessive binding of Plasmodium falciparum-infected erythrocytes to the microvascular endothelium (cytoadherence) and to uninfected eryrthrocytes (rosetting) are regarded as key-events in the development of a severe malaria infection. P. falciparum rosetting was confirmed to be associated with the development of cerebral malaria in The Gambia. LÄS MER

  3. 2. Immunoglobulins in the adhesion of Plasmodium falciparum-infected erythrocytes in malaria

    Författare :Carin Scholander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Plasmodium falciparum; rosetting; cytoodhesion; immunoglobulins; serum proteins; fibrillar structures; malarial anaemia; placental malaria; PfEMP1;

    Sammanfattning : Characterisation of the delicate cell-to-cell interactions involved in the binding of Plasmodium falciparum- infected erythrocytes to host cells is central for the understanding of the development of severe malaria. Infected erythrocytes adhere in the deep vasculature of several organs, sequestration, leading to cerebral malaria, pulmonary oedema or renal failure. LÄS MER

  4. 3. Parasite antigens and cellular interactions associated with the membrane of Plasmidium falciparum infected erythrocytes

    Författare :Wipaporn Ruangjirachuporn; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The asexual erythrocytic stages of malaria parasites are the cause of the pathological manifestations of the disease, Plasmodium falciparum being the species notorious for causing serious complications. This thesis describes studies on parasite-host cell interactions at two different stages of the P. LÄS MER

  5. 4. Nature and functions of Plasmodium falciparum malaria antigens associated with the membrane of infected erythrocytes

    Författare :Rachanee Udomsangpetch; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  7. 5. Variable surface molecules of the plasmodium falciparum infected erythrocyte and merozoite

    Författare :Malin Haeggström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :P.falciparum; infected erythrocytes; transport; Maurer s clefts; antigenic variation; PfEMP1; RIFIN; SURFIN; merozoites; subgroups;

    Sammanfattning : As Plasmodium falciparum parasites matures within the infected erythrocyte (IE) it produces a number of various proteins, which are transported out to the cell surface where they are exposed to the host immune system. To avoid recognition and elimination by the liver and spleen these proteins can undergo antigenic variation, a phenomenon where the parasites switch from expressing one variant to' another, both belonging to the same gene-family. LÄS MER