Sökning: "in-situ"

Visar resultat 1 - 5 av 1903 avhandlingar innehållade ordet in-situ.

1. 1. In situ Sequencing : Methods for spatially-resolved transcriptome analysis

   Författare :Marco Mignardi; Mats Nilsson; Xiaoliang Sunney Xie; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Padlock probes; rolling circle amplification; in situ sequencing; spatially-resolved transcriptomics; molecular diagnostics; Biochemistry; biokemi;

   Sammanfattning : It is well known that cells in tissues display a large heterogeneity in gene expression due to differences in cell lineage origin and variation in the local environment at different sites in the tissue, a heterogeneity that is difficult to study by analyzing bulk RNA extracts from tissue. Recently, genome-wide transcriptome analysis technologies have enabled the analysis of this variation with single-cell resolution. LÄS MER

3. 2. Visualizing Interacting Biomolecules In Situ

   Författare :Irene Weibrecht; Ola Söderberg; Ulf Landegren; Banafshe Larijani; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proximity ligation; in situ PLA; padlock probe; rolling circle amplification; flow cytometry; in situ; single cell; single molecule; protein interaction; protein-DNA interaction; posttranslational modification; Molecular medicine; Molekylär medicin; Molekylär medicin; Molecular Medicine;

   Sammanfattning : Intra- and intercellular information is communicated by posttranslational modifications (PTMs) and protein-protein interactions, transducing information over cell membranes and to the nucleus. A cells capability to respond to stimuli by several highly complex and dynamic signaling networks provides the basis for rapid responses and is fundamental for the cellular collaborations required in a multicellular organism. LÄS MER

4. 3. Analysis of Arctic ice cloud properties using in-situ and remote sensing measurements

   Författare :Veronika Wolf; Thomas Kuhn; Peter Völger; Martin Gallagher; Luleå tekniska universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Arctic cirrus clouds; ice particle properties; in-situ measurements; in-situ and lidar comparison; Atmospheric science; Atmosfärsvetenskap;

   Sammanfattning : Cirrus clouds play an important role in the radiation balance of the atmosphere as theycan have a warming and cooling effect. The resulting net radiation effect depends ontheir micro- and macrophysical properties such as particle size, shape, and numberconcentration. LÄS MER

5. 4. Genotyping and Mutation Detection In Situ : Development and application of single-molecule techniques

   Författare :Ida Grundberg; Mats Nilsson; Ulf Landegren; Olli-Pekka Kallioniemi; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; padlock probes; in situ; rolling circle amplification; mRNA; genotyping; mutation detection; cancer; tissue sections; diagnostics; single-molecule; single-cell; microscopy; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Molekylär medicin; Molecular Medicine;

   Sammanfattning : The human body is composed of trillions of cells closely working together to maintain a functional organism. Every cell is unique in molecular composition and can acquire genetic variations that might cause it to turn pathological. LÄS MER

7. 5. In-situ TEM Probing of Nanomaterials

   Författare :Magnus Hummelgård; Håkan Olin; Valeria Nicolosi; Mittuniversitetet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; nanotechnology; in situ; TEM; probing; nanowires; nanoparticles; ink; Other engineering physics; Övrig teknisk fysik; Material physics with surface physics; Materialfysik med ytfysik; Condensed matter physics; Kondenserade materiens fysik;

   Sammanfattning : Nanomaterials because of their small size, may have special properties unlikely to be seen in ordinary types of materials. Nanomaterials like nanotubes,nanowires and nanoparticles are best studied at the nanoscale, vital but also problematic. LÄS MER