Sökning: "in-situ hybridization"

Visar resultat 1 - 5 av 267 avhandlingar innehållade orden in-situ hybridization.

  1. 1. Expression and Mutation Analyses of Candidate Cancer Genes In Situ

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Sara Kiflemariam; Uppsala universitet.; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; in situ; in situ hybridization; padlock probes; mRNA; tyrosine kinases; tyrosine phosphatases; fusion transcripts;

    Sammanfattning : Cancers display heterogeneity in genetic profiles of the individual cancer cells and in the composition of different malignant and non-malignant cell populations. Such intra-tumor heterogeneity plays a role in treatment response and the emergence of resistance to cancer therapies. LÄS MER

  2. 2. Neuropeptide Y Receptors in Human, Guinea pig and Chicken Cloning, in vitro Pharmacology and in situ Hybridization

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Sara Holmberg; Uppsala universitet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; G-protein coupled receptor; neuropeptide Y; neuropeptide Y receptor; ortholog; chicken; guinea pig; mutagenesis; receptor computer modeling; mRNA in situ hybridization; Neurovetenskap; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Neuropeptide Y (NPY) is known to influence a vast number of physiological and behavioral processes such as vasoconstriction, circadian rhythms, feeding, anxiety and memory. Peptides of the NPY family bind to five different cloned G-protein coupled receptor subtypes (Y1, 2, 4-6). LÄS MER

  3. 3. Telomere analysis of normal and neoplastic hematopoietic cells studies focusing on fluorescence in situ hybridization and flow cytometry

    Detta är en avhandling från Umeå : Medicinsk biovetenskap

    Författare :Magnus Hultdin; Umeå universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicine; telomere; telomerase; fluorescence in situ hybridization; flow cytometry; flow-FISH; replication timing; chronic lymphocytic leukemia; immunoglobulin gene; prognosis; Biomedicin; MEDICINE Microbiology; immunology; infectious diseases Microbiology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi; Medical Cell Biology; medicinsk cellbiologi;

    Sammanfattning : The telomeres are specialized structures at the end of the chromosomes composed of the repeated DNA sequence (TTAGGG)n and specific proteins bound to the DNA. The telomeres protect the chromosomes from degradation and end to end fusions. LÄS MER

  4. 4. Genetic characterization of non-Hodgkin lymphomas using in situ hybridization

    Detta är en avhandling från Stockholm : Karolinska Institutet, false

    Författare :Svetlana Lagercrantz; Karolinska Institutet.; Karolinska Institutet.; [1996]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Myelodysplastic syndrome; non-Hodgkin lymphoma; fluorescencein situ hybridization; LAZ3BCL6 expression; chromosome rearrangements;

    Sammanfattning : Fluorescence in situ hybridization (FISH) has been shown to be a valuable andimportant technique in cytogenetics, as a complement to traditional bandinganalysis. This thesis focus on the characterization of chromosomalrearrangements in two hematological neoplasias, myelodysplastic syndrome(MDS) and non-Hodgkin lymphoma (NHL) using FISH. LÄS MER

  5. 5. Improvements and Applications of in situ Proximity Ligation Assays

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Karin Grannas; Uppsala universitet.; [2015]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molekylär medicin; Molecular Medicine;

    Sammanfattning : The cells building up the human body is in constant communication with each other. This communication is done through large complex networks of signaling pathways for inter- and intracellular signal transduction. The signaling activity regulates many important processes, for example cell death, proliferation and differentiation. LÄS MER