Sökning: "immunohistochemistry IHC"
Visar resultat 1 - 5 av 95 avhandlingar innehållade orden immunohistochemistry IHC.
1. Prognostic and Predictive Factors in Bladder Cancer
Sammanfattning : Bladder cancer is a potentially curable malignancy; however in regards to the state of current therapy regimens, a plateau has been reached in both the non-muscle and muscle invasive types. To obtain effective treatment, and consequently a decreased mortality, it has become imperative to test and understand aspects affecting therapy response. LÄS MER
2. Proteomic Analysis of Urinary Bladder Cancer : Aiming for Novel Biomarkers
Sammanfattning : Urinary bladder cancer is a heterogeneous disease appearing in different forms, e.g. non-muscle invasive and muscle invasive. For all variants, the expression of proteins is interesting to analyze for diagnostic, predictive, prognostic and drug targeting purposes, since it reflects the altered gene expression causing the cancer. LÄS MER
3. Validation of antibodies for protein profiling : A study using immunohistochemistry on tissue microarrays
Sammanfattning : The field of proteomics has rapidly expanded due to the completion of the human genome sequence. This thesis validates affinity-purified monospecific antibodies of polyclonal origin, for protein profiling in a broad spectrum of normal tissues and cells. LÄS MER
4. Clinical significance of immunohistochemistry in breast cancer diagnostics
Sammanfattning : For patients with breast cancer, modern patient-tailored treatment depends on tumor- specific characteristics, i.e., estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor 2 (HER2), and the proliferation marker Ki67. LÄS MER
5. Quantitative immunochemistry in tissue sections : With special reference to urinary bladder carcinoma
Sammanfattning : Urinary bladder carcinoma affects about 2 000 people in Sweden every year. It is a heterogeneous disease and for adequate treatment decisions, prognostic tools are needed. Many of these are based on immunohistochemistry (MC) and hampered by poorly reproducible methodologies and subjective evaluations. LÄS MER