Sökning: "hyphenated techniques"

Hittade 5 avhandlingar innehållade orden hyphenated techniques.

  1. 1. Large Volume Injection and Hyphenated Techniques for Gas Chromatographic Determination of PBDEs and Carbazoles in Air

    Författare :Petter Tollbäck; Conny Östman; Tuulia Hyötyläinen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; large volume injection; hyphenated techniques; LC-GC; GC-MS; mass spectrometry; GC; gas chromatography; carbazoles; PBDE; polybrominated diphenyl ethers; Analytical chemistry; Analytisk kemi;

    Sammanfattning : This thesis is based on studies in which the suitability of various gas chromatography (GC) injection techniques was examined for the determination of polybrominated diphenyl ethers (PBDEs) and carbazoles, two groups of compounds that are thermally labile and/or have high boiling-points. For such substances, it is essential to introduce the samples into the GC system in an appropriate way to avoid degradation and other potential problems. LÄS MER

  3. 2. On the reliability of methods for the speciation of mercury based on chromatographic separation coupled to atomic spectrometric detection

    Författare :Johanna Qvarnström; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Mercury; speciation; hyphenated techniques; HPLC; CE; GC; CV-AAS; ICP-MS; species-specific enriched stable isotope; Analytisk kemi; Analytical chemistry; Analytisk kemi; analytisk kemi; Analytical Chemistry;

    Sammanfattning : This thesis deals with the reliability of methods for the speciation of mercury in environmental and biological samples. Problems with speciation methods that couple chromatography to atomic spectrometric detection and how to overcome the problems are discussed. LÄS MER

  4. 3. Advances in analytical methodologies for studies of the platinum metallome in malignant cells exposed to cisplatin

    Författare :Yvonne Nygren; Erik Björn; Knut Irgum; Bente Gammelgaard; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Method development; Metallome; Inductively coupled plasma mass spectrometry; Electrospray ionization mass spectrometry; Liquid chromatography; Hyphenation; Organic modifier; Cisplatin; Platinum; Analytical chemistry; Analytisk kemi; analytisk kemi; Analytical Chemistry;

    Sammanfattning : The scientific progress about the important chemotherapeutic drug substance cisplatin (CDDP) and its function has often been rendered by data difficult to interpret, and still many questions about its mode of action remains to be clarified by the scientific community. However, studies of CDDP possess a high complexity due to; i) low intracellular concentration, ii) many potential biomolecule targets, iii) poor or unknown stability of the intact drug and its biomolecule adducts and iv) complex and varying sample matrices. LÄS MER

  5. 4. Instrumental and methodological developments for isotope dilution analysis of gaseous mercury species

    Författare :Tom Larsson; Erik Björn; Holger Hintelmann; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mercury; gas; species; speciation analysis; isotope dilution analysis; permeation tubes; Analytical chemistry; Analytisk kemi;

    Sammanfattning : This thesis deals with instrumental and methodological developments for speciation analysis of gaseous mercury (Hg(g)), based on isotope dilution analysis (IDA). The studied species include Hg0, (CH3)2Hg, CH3HgX and HgX2 (where X symbolises a negatively charged counter ion in the form of a halide or hydroxyl ion). LÄS MER

  7. 5. Chemometrics : Unravelling information from complex data generated by modern instruments

    Författare :Pedro F. M. de Sousa; Magnus Åberg; Johan Trygg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemometrics; Chromatography; Mass spectrometry; DIA; PCA; PLS; Experimental Design; DNA; adductomics; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Chemometrics is a discipline dedicated to solving problems arising from complicated analytical systems, combining statistics, mathematics, and computational programming languages.This thesis is based on the work developed in four scientific projects published as papers in scientific journals. LÄS MER