Sökning: "hypercoagulable state"
Visar resultat 1 - 5 av 8 avhandlingar innehållade orden hypercoagulable state.
1. Arterial Thrombosis in Factor V Leiden or Activated Protein C Resistance. Clinical and Experimental Studies
Sammanfattning : Abstract The last two decades has seen an avalanche of studies establishing Activated protein C (APC) resistance due to Factor V Leiden mutation as the most prevalent genetic risk factor, yet known, for venous thromboembolism. This has been documented in 20-60% of patients with deep vein thrombosis (DVT). LÄS MER
2. Troponin elevation in acute stroke : clinical characteristics and the link to cancer-associated neutrophil extracellular traps
Sammanfattning : Elevated plasma levels of troponin, a marker of myocardial injury, are a frequent observation in stroke patients. Despite several reports on an adverse short-term prognosis, however, the significance of troponin elevation in stroke is still controversial, and the myocardial injury often lacks a clear etiology. LÄS MER
3. Resistance to activated protein C a novel risk factor for venous thrombosis
Sammanfattning : Activated protein C resistance (APC resistance) is the most common hereditary condition associated with venous thrombosis. The syndrome known as APC resistance is perfectly linked to a mutation in the gene coding coagulation FV (FV:Q506) mutation changing Arg 506 to Gln in the APC cleavage site. LÄS MER
4. Hypercoagulation in preeclampsia : implications for maternal health and fetal growth
Sammanfattning : Background: Preeclampsia (PE) is a serious complication of pregnancy characterized by hypertension, proteinuria, oedema and hypercoagulation. Damage in organs, such as the liver and kidney, is harmful to the maternal health. Impairments in placental function cause intrauterine growth retardation (IUGR). LÄS MER
5. Microparticles in hemophilia : friend or foe? To improve hemostasis or to induce atherothrombosis?
Sammanfattning : As one of the most well-known inherited bleeding disorders, hemophilia A (HA) is caused by the deficiency or dysfunction of coagulation factor VIII (FVIII). Patients with HA (PWHA) suffer from abnormal bleeding after injuries or surgeries, or even spontaneous bleeding in severe cases, particularly at joints and muscles. LÄS MER