Sökning: "human leukocyte proteases"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden human leukocyte proteases.
1. Experimental and Clinical Studies of SLPI, with Special Reference to IgE-Mediated Allergic Reactions
Sammanfattning : In this study we demonstrated the production of SLPI (Secretory Leukocyte Protease Inhibitor) in serous glands in the nasal mucosa. We have shown that the pattern of the expression of mRNA corresponds to the encoded protein. The encoded protein was detected by immunohistochemical methods and mRNA was discovered by in situ hybridisation. LÄS MER
2. Secretory Leukocyte Protease Inhibitor (SLPI) in the gastrointestinal tract in man
Sammanfattning : Secretory leukocyte protease inhibitor is a 11.7 kDa acid stable serine protease inhibitor. SLPI has been shown to be the dominant protease inhibitor in bronchial secretions and has been used in treatment of pulmonary emphysema. LÄS MER
3. OVULATION: Intra-ovarian mechanisms
Sammanfattning : Background: Ovulation is the central biological process involved in the menstrual cycle of women. Specifically, ovulation involves the tissue remodelling of the preovulatory follicle to achieve the rupture of the exterior follicle wall with the extrusion of the oocyte. LÄS MER
4. Serine protease inhibitors in the upper and lower airways
Sammanfattning : Proteases and their inhibitors are implicated in the physiology and pathology of the airways. Protease inhibitors include those produced locally, such as secretory leukocyte protease inhibitor (SLPI), and those produced mainly by the liver that can reach the airways via passive diffusion, such as alpha1-antitrypsin (AAT). LÄS MER
5. The Role of Matrix Metalloproteinases in Leukocyte Transmigration in Murine Experimental Autoimmune Encephalomyelitis
Sammanfattning : Murine experimental autoimmune encephalomyelitis (EAE) is a commonly used model in the investigation of the human disease multiple sclerosis (MS), a debilitating inflammatory disease of the central nervous system (CNS). MS and EAE involve multiple steps, primarily, auto-antigenic leukocyte (mainly T-cells and macrophages) crossing the blood-brain barrier and later their invasion into the CNS where they degrade myelin basic protein, eventually resulting in axonal degradation and CNS inflammation. LÄS MER