Sökning: "huang"

Visar resultat 1 - 5 av 119 avhandlingar innehållade ordet huang.

  1. 1. Functional genomics approaches to dissect causal DNA variations in obesity and type 2 diabetes

    Författare :Mi Huang; Genetisk och molekylär epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GWAS; Obesity; Type 2 diabetes; CRISPR Cas9; precision medicine; adipocytes; functional genomics;

    Sammanfattning : GWAS studies have identified hundreds of loci that associate with obesity and type 2 diabetes. However, the functional relevance of the genetic variants, and their impact on disease or traits, is largely unknown. LÄS MER

  3. 2. Glucose and glycerol transport in adipocytes from a structural perspective

    Författare :Peng Huang; Medicinsk strukturbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocytes; glucose and glycerol metabolism; glucose transporters; aquaglyceroporins; glucose transporter 4; aquaglyceroporin 7; protein and protein interaction; structure; single particle cryo-EM;

    Sammanfattning : Adipocytes are crucial energy reservoirs to maintain metabolic homeostasis of glucose and lipids in the human body.Glucose transporters (GLUTs) and aquaporins (AQPs) play an important role in metabolic regulation of glucose andlipids in human adipocytes. LÄS MER

  4. 3. Geospatial data and knowledge on the Web : Knowledge-based geospatial data integration and visualisation with Semantic Web technologies

    Författare :Weiming Huang; Institutionen för naturgeografi och ekosystemvetenskap; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Geospatial data integration; data visualisation; Semantic Web; Linked Data; ontology;

    Sammanfattning : Geospatial information is indispensable for various types of spatially informed analysis and decision-making, such as traffic analyses, and natural resource management. In addition, geospatial information is one of the most powerful information integrators to bridge diverse sources of information. LÄS MER

  5. 4. On the inception of leakage : Effect of hydrostatic pressure on the sealing interface

    Författare :De Huang; Andreas Almqvist; Roland Larsson; Xiang Yan; Alessandro Ruggiero; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; static seal; contact mechanics; hydrostatic; critical pressure; leakage; Maskinelement; Machine Elements;

    Sammanfattning : As the move towards sustainability continues,  attention needs to be paid to the development of new machinery with high performance and low environmental impact. It places increasing demands on low/zero-emission sealing with a long lifetime. LÄS MER

  7. 5. Epidemiology and etiology of pancreatic cancer

    Författare :Jiaqi Huang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Pancreatic cancer is one of the most devastating malignancies with an extremely high fatality, resulting that its mortality rate almost equals to incidence rate. Although primary prevention is of upmost importance, the underlying etiology of this cancer remains largely unknown. LÄS MER