Sökning: "host response"

Visar resultat 16 - 20 av 676 avhandlingar innehållade orden host response.

  1. 16. The interplay between Giardia intestinalis and host intestinal epithelial cells : A tale of immune activation and suppression

    Författare :Jana Grüttner; Staffan Svärd; Mikael E. Sellin; Steven Singer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Giardia; diarrhea; RNAseq; proteomics; small intestinal epithelial cells; enteroids; organoids; protozoan; differentiation; immune response; host-parasite interaction; swimming; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : Giardia intestinalis is a non-invasive, protozoan parasite causing the diarrheal disease giardiasis in a variety of mammals, including humans. The parasite has two main life cycle stages; disease-causing trophozoites and infectious cysts. Trophozoites colonize the host’s upper small intestine by attaching to intestinal epithelial cells (IECs). G. LÄS MER

  3. 17. Host-Pathogen Responses during Giardia infections

    Författare :Emma Ringqvist; Staffan Svärd; Patricia Johnson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Giardia; parasite infection; host-parasite releationship; immune activation; virulence factor; immune evasion; Cell and molecular biology; Cell- och molekylärbiologi; Microbiology; Mikrobiologi; mikrobiologi; Microbiology;

    Sammanfattning : Giardia lamblia is a eukaryotic parasite of the upper small intestine of humans and animals. The infecting trophozoite cells do not invade the epithelium lining of the intestine, but attach to the brush border surface in the intestinal lumen. The giardiasis disease in humans is highly variable. LÄS MER

  4. 18. Faecal Microbiota Transfer in Irritable Bowel Syndrome and Collagenous Colitis : Clinical outcomes and host-microbe interactions

    Författare :Savanne Holster; Robert Jan Brummer; Julia König; Andreas Munk Petersen; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Faecal microbiota transfer; irritable bowel syndrome; collagenous colitis; gut microbiota; visceral sensitivity; host-microbe interactions; gene expression; metabolites;

    Sammanfattning : Faecal microbiota transfer (FMT) aims at restoring a disturbed gut microbiotaby introducing faecal material from a healthy donor into a patient’s intestine. This approach is known as a safe and effective treatment in patients with recurrent Clostridioides difficile infection. LÄS MER

  5. 19. Staphylococcus aureus bacteremia, molecular epidemiology and host immune response

    Författare :Gunlög Rasmussen; Bo Söderquist; Kristoffer Strålin; Eva Särndahl; Peter Bergman; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Staphylococcus aureus; molecular epidemiology; DNAmicroarray; bacteremia; sepsis; NLRP3; inflammasome; caspase-1; HLA-DR; HLA-DRA; CD74;

    Sammanfattning : Staphylococcus aureus is a major pathogen responsible for a considerable disease burden worldwide. It may cause a wide array of infections, from superficial skin infections to invasive bacteremia and complications such as infective endocarditis (IE) and osteomyelitis. This thesis aimed to investigate aspects of the molecular epidemiology of S. LÄS MER

  7. 20. ESBL-producing Enterobacterales - Transmission, intestinal colonization and host response

    Författare :Oskar Ljungquist; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ESBL; antibiotikaresistens; E. coli;

    Sammanfattning : .... LÄS MER