Sökning: "homology"

Visar resultat 1 - 5 av 328 avhandlingar innehållade ordet homology.

  1. 1. Khovanov Homology and Link Cobordisms

    Författare :Magnus Jacobsson; Oleg Viro; Jan-Erik Roos; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Algebra and geometry; Khovanov homology; Jones polynomial; Link cobordisms; Algebra och geometri; Algebra and geometry; Algebra och geometri;

    Sammanfattning : Khovanov homology associates to any link in three-dimensional space a bigraded chain complex of Z[c]-modules, whose graded Euler characteristic (after normalization) is the Jones polynomial of the link. The complex is invariant up to homotopy equivalence under ambient isotopy of the link. LÄS MER

  3. 2. Protein structure prediction : Zinc-binding sites, one-dimensional structure and remote homology

    Författare :Nanjiang Shu; Sven Hovmöller; Bruce Donald; Geoff Barton; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; protein structure prediction; zinc-binding; profile; homology detection; shape string; Bioinformatics; Bioinformatik; Molecular biology; Molekylärbiologi; Biochemistry; Biokemi; Structural Chemistry; strukturkemi;

    Sammanfattning : Predicting the three-dimensional (3D) structure of proteins is a central problem in biology. These computationally predicted 3D protein structures have been successfully applied in many fields of biomedicine, e.g. family assignments and drug discovery. LÄS MER

  4. 3. The relationship between orthology, protein domain architecture and protein function

    Författare :Kristoffer Forslund; Erik Sonnhammer; Cristina Al-Khalili Szigyarto; Sarah Teichmann; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; homology; orthology; paralogy; gene duplications; protein function prediction; low-complexity regions; protein domains; domain architecture evolution; introns; intron position conservation; orthology conjecture; domain grammar hypothesis; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

    Sammanfattning : Lacking experimental data, protein function is often predicted from evolutionary and protein structure theory. Under the 'domain grammar' hypothesis the function of a protein follows from the domains it encodes. LÄS MER

  5. 4. (Co)homology of Monomial Algebras

    Författare :Emil Sköldberg; Jürgen Herzog; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MATHEMATICS; MATEMATIK; matematik; Mathematics;

    Sammanfattning : .... LÄS MER

  7. 5. Sequence-based predictions of membrane-protein topology, homology and insertion

    Författare :Andreas Bernsel; Gunnar von Heijne; Volkhard Helms; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; membrane protein; topology prediction; hidden markov model; homology detection; Sec translocon; Bioinformatics; Bioinformatik; Biochemistry; biokemi;

    Sammanfattning : Membrane proteins comprise around 20-30% of a typical proteome and play crucial roles in a wide variety of biochemical pathways. Apart from their general biological significance, membrane proteins are of particular interest to the pharmaceutical industry, being targets for more than half of all available drugs. LÄS MER