Sökning: "high blood glucose"

Visar resultat 1 - 5 av 263 avhandlingar innehållade orden high blood glucose.

  1. 1. Glucose and lipid metabolism in insulin resistance : an experimental study in fat cells

    Författare :Jonas Burén; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; adipocyte; insulin resistance; type 2 diabetes; insulin signalling; glucose uptake; insulin; glucose; dexamethasone; insulin receptor substrate; protein kinase B; GLUT4; lipoprotein lipase; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden; medicin; Medicine;

    Sammanfattning : Type 2 diabetes is usually caused by a combination of pancreatic β-cell failure and insulin resistance in target tissues like liver, muscle and fat. Insulin resistance is characterised by an impaired effect of insulin to reduce hepatic glucose production and to promote glucose uptake in peripheral tissues. LÄS MER

  2. 2. Quantitation, Purification and Reconstitution of the Red Blood Cell Glucose Transporter GLUT1

    Författare :Shusheng Zuo; Bengt Mannervik; Bengt Persson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Cholesterol; Cytochalasin B; Glucose; GLUT1; Hummel and Dreyer analysis; Immobilization; PEG 5000 -DSPE; Biomembrane; Proteoliposome; Quantitative frontal affinity chromatography; Red blood cell streptavidin-biotin immobilization; Sulfhydryl affinity chromatography; The modified micro-Bradford CaPE assay; MALDI-ToF-MS; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : The human glucose transporter GLUT1 facilitates glucose to be accumulated on the other side of the cell membrane. The functional state of GLUT1 is uncertain due to diversity of the reports. In this thesis, the activity of red blood cell GLUT1 was extensively studied to further characterize this protein. LÄS MER

  3. 3. Oxidative stress and inflammation as a response to glucose exposure and dialysis

    Författare :Anna Bryland; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucose; glucose degradation products; dialysis; diabetes; oxidative stress; inflammation; endothelial dysfunction;

    Sammanfattning : Abstract: The main player of this thesis is glucose, both on a cellular level and with a clinical approach. Too much or wrongly handled glucose contributes to increased inflammation and oxidative stress, which is reinforced by the negative influences of uraemia and dialysis treatment. LÄS MER

  4. 4. Dental Health Care Cooperating with Primary Health Care as a Resource in Early Case Finding of Patients with Diabetes or Hypertension

    Författare :Sevek Engström; Kurt Svärdsudd; Christian Berne; Lars Gahnberg; Margareta Kristenson; Uppsala universitet; []
    Nyckelord :Screening; dental care; primary health care; high blood pressure; high blood glucose; Family Medicine; Allmänmedicin;

    Sammanfattning : Objectives To investigate if there is an association between dental health status and high blood pressure, to test the effectiveness of screening for high blood pressure and high blood glucose performed by the dental health care in collaboration with primary health care and to investigate the direct costs for this type of screening organisation. Study population and methods In Paper I 54 subjects with known hypertension and 141 with a high blood pressure in the dental office were compared with matched controls. LÄS MER

  5. 5. Heritability of blood pressure: monogenes and polygenes

    Författare :Cristiano Fava; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Biomedicinska vetenskaper; Biomedical sciences; kidney; Adducin-1; CLC-kb; Gitelman syndrome; association; heritabilty; genetics; hypertension; Blood pressure; blood pressure variability; Medicin människa och djur ; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : High blood pressure (BP) is associated with cardiovascular morbidity and mortality. Both genetic and environmental factors are implicated in BP homeostatsis and hypertension development. LÄS MER