Sökning: "heredity"

Visar resultat 1 - 5 av 93 avhandlingar innehållade ordet heredity.

1. 1. Colorectal Cancer : Aspects of Heredity, Prognosis and Tumour Markers

   Författare :Lana Ghanipour; Helgi Birgisson; Lars Påhlman; Karin Jirström; Tom Öresland; Uppsala universitet; []
   Nyckelord :colorectal cancer; heredity; Tryptophanyl t-RNA synthetase; microsatellite instability; SP-PLA; prognosis; biomarkers;

   Sammanfattning : Colorectal cancer (CRC) is one of the most common cancer types and leading causes of cancer death worldwide. Since CRC is a heterogenic disease, there is a demand for increased knowledge of the underlying genetic and epigenetic mechanisms. The aim of this thesis was to investigate heredity and potential tumour markers in relation to prognosis. LÄS MER

3. 2. On the occurrence and possible causes of motor neuron disease in Sweden

   Författare :Lars-Gunnar Gunnarsson; Linköpings universitet; []
   Nyckelord :Epidemiology; amyotrophic lateral sclerosis; incidence; prevalence; mortality; cluster; Iisk factors; occupation; environment; agricultural work; electrical work; welding; solvents; heredity; MEDICINE; MEDICIN;

   Sammanfattning : A series of investigations have been performed to study secular trends of motor neuron disease (MND) morbidity and mortality in Sweden, to identify time and/or space clusters, if any, and to uncover risk factors. The occurrence of the disease was estimated from incidence, prevalence and mortality rates, and the strength of various determinants was evaluated by means of the case-control approach, using population controls. LÄS MER

4. 3. Insights into breast cancer: New familial patterns and identification of a potential predictive marker

   Författare :Carolina Ellberg; Tumörmikromiljö; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; BRCA1; BRCA2; Spider telangiectasias; Heredity; Parental inheritance; Recessive; familial; Breast cancer;

   Sammanfattning : The last proportion of heredity in breast cancer has proven to be somewhat elusive despite massive attempts to identify the associated factors. Approximately 50 percent of breast cancer caused by familial factors is currently explained. LÄS MER

5. 4. Tourette Syndrome and Tic Disorders in a Swedish School Population : Prevalence, Clinical Assessment, Background, Psychopathology, and Cognitive Function

   Författare :Najah Khalifa; Anne-Liis von Knorring; Claes Sundelin; Elisabeth Fernell; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Child and adolescent psychiatry; Tourette syndrome; tic disorders; population study; psychopathology; heredity; perinatal complications; cognitive function; Barn- och ungdomspsykiatri; Child and adolescent psychiatry; Barn- och ungdomspsykiatri; Child and Youth Psychiatry; Barn- och ungdomspsykiatri;

   Sammanfattning : A total population of 4,479 children (7-15 years of age) attended school in Ludvika & Smedjebacken in 2000. All the school children and their parents were asked to fill in a questionnaire concerning different tics A three-stage procedure was used: tic identification, interview, and clinical assessment. LÄS MER

7. 5. Cancer risk and predisposition in families with childhood cancer

   Författare :Karl-Johan Stjernfelt; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Pediatric; Childhood Cancer; Heredity; Genetics; predisposition; Familial cancer;

   Sammanfattning : BACKGROUND: Recent whole genome sequencing studies report that up to 6% of the childhood cancer population harbour a pathogenic variant. Identification of families with hereditary cancer may improve early detection of cancer as well as treatment outcome. LÄS MER