Sökning: "hepatocellular cancer"

Visar resultat 26 - 30 av 57 avhandlingar innehållade orden hepatocellular cancer.

  1. 26. Harnessing T cell immunity for the prevention and treatment of liver cancer

    Författare :Panagiota Maravelia; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hepatocellular carcinoma (HCC) accounts for more than 80% of all diagnosed cases of liver cancer which is a major cause of cancer related fatalities worldwide. With few improvements in the survival rates during the last decades, prevention of HCC is key in reducing its burden globally. LÄS MER

  3. 27. Oxidative stress in cell and tissue damage and selenium-based therapeutics in cancer

    Författare :Rim Jawad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Redox homeostasis is the balance between cellular prooxidants and antioxidants, maintained by the interplay of electrons. Reactive oxygen species (ROS) is a term for molecules with unpaired valence electrons or unstable bonds. LÄS MER

  4. 28. Signalomics : unsupervised and global strategies to explore mechanisms of radioresistence in lung cancer cells

    Författare :Sara Ståhl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : To combat lung cancer (LC) which is the number one cancer associated killer, a combination of surgery, chemotherapy, radiotherapy and targeted agents are currently used. The main subtype of LC, Non small cell lung cancer (NSCLC) unfortunately responds poorly to conventional radiotherapy (RT) for reasons yet only partly understood. LÄS MER

  5. 29. Prevention of liver cancer in chronic liver disease : an experimental study of sodium selenite and rat hepatocarcinogenesis

    Författare :Suvd Erkhembayar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Selenium treatment in supranutritional but subtoxic doses has previously been shown to inhibit cell proliferation in preneoplastic lesions in a rat liver carcinogenesis model. The mechanisms are not known, but thioredoxin reductase (TrxR1), a seleno-enzyme essential for maintaining intracellular redox status and cellular defence against oxidative stress might be involved. LÄS MER

  7. 30. Risk of hepatocellular carcinoma, liver-related complications, and death in persons living with chronic hepatitis B and D

    Författare :Habiba Kamal; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic hepatitis B virus (HBV) infection affects 257 million individuals and is a leading cause of liver-related morbidity and mortality. Hepatitis D virus (HDV) is a satellite virus, that needs HBV for packing and propagation, hence infecting only individuals with HBV infection. LÄS MER