Sökning: "hemostasis"

Visar resultat 1 - 5 av 57 avhandlingar innehållade ordet hemostasis.

1. 1. Unstable coronary artery disease : Studies on inflammation, infection, hemostasis, and the effects of low-molecular-mass heparin treatment

   Författare :Henrik Toss; Uppsala universitet; []
   Nyckelord :Medical sciences; unstable angina; myocardial infarction; prognosis; inflammation; hemostasis; fibrinolysis; resistance to activated protein C. low-molecular-mass heparin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : The occurrence and prognostic importance, of inflammatory activity, signs of Chlamydia pneumoniae infection. APC resistance, hemostasis, and the effects of low-molecular-mass heparin (LMMH) was evaluated in patients with unstable coronary artery disease (UCAD). LÄS MER

3. 2. Fibrinogen and Bleeding in Cardiac Surgery: Clinical Studies in Coronary Artery Bypass Patients

   Författare :Martin Karlsson; Göteborgs universitet; []
   Nyckelord :Cardiac surgery; Hemostasis; Cardiopulmonary bypass; Fibrinogen; Bleeding;

   Sammanfattning : Fibrinogen and Bleeding in Cardiac Surgery: Clinical Studies in Coronary Artery Bypass Patients Background: Cardiac surgery is accompanied by inflammatory activation and bleeding complications. Fibrinogen is a key factor in the coagulation cascade and can be used to treat ongoing bleeding, but is not well studied as prophylactic treatment to prevent bleeding in patients with normal plasma fibrinogen levels or as a predictive tool to identify patients with increased bleeding risk. LÄS MER

4. 3. The Plasma Contact System : New Functional Insights from a Hemostatic and Thrombotic Perspective

   Författare :Jennie Bäck; Bo Nilsson; Kristina Nilsson Ekdahl; Ulla Hedner; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Contact activation; factor XII; platelets; coagulation; antithrombin; C1 inhibitor; hemostasis; biomarkers; vascular disease.; Klinisk immunologi; Clinical Immunology;

   Sammanfattning : The physiological role of the plasma contact system still remains a partial enigma. The aim of the presented work was to expand our understanding of the plasma contact system, focusing on its physiological activation and function, principally from a hemostatic perspective. It also explored contact system activation under pathological conditions. LÄS MER

5. 4. Cardiopulmonary bypass: Clinical studies in cardiac surgery patients

   Författare :Mikael Barbu; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiopulmonary bypass; Cardiac surgery; Colloid; Prime; Acute kidney injury; Brain injury marker; Hemostasis;

   Sammanfattning : BACKGROUND: Cardiopulmonary bypass (CPB) is necessary to facilitate most cardiac operations. Although the vast majority of patients tolerate CPB physiology in conjunction with cardiac surgery well, there is risks of adverse outcomes. Optimal CPB perfusion is not defined, and may vary according to operation and patient specific factors. LÄS MER

7. 5. On the role of genetic variation and epigenetics in hemostatic gene regulation

   Författare :Martina Olsson Lindvall; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hemostasis; Tissue-type plasminogen activator; Genetics; Epigenetics; DNA methylation;

   Sammanfattning : Many genetic variants have been identified to associate with circulating levels of hemostatic proteins and with thrombotic or hemorrhagic disorders. However, the underlying molecular mechanisms remain largely unknown. LÄS MER