Sökning: "glucose signalling"
Visar resultat 1 - 5 av 106 avhandlingar innehållade orden glucose signalling.
1. Glucose and lipid metabolism in insulin resistance : an experimental study in fat cells
Sammanfattning : Type 2 diabetes is usually caused by a combination of pancreatic β-cell failure and insulin resistance in target tissues like liver, muscle and fat. Insulin resistance is characterised by an impaired effect of insulin to reduce hepatic glucose production and to promote glucose uptake in peripheral tissues. LÄS MER
2. β-Adrenergic Signalling Through mTOR
Sammanfattning : Adrenergic signalling is part of the sympathetic nervous system and is activated upon stimulation by the catecholamines epinephrine and norepinephrine. This regulates heart rate, energy mobilization, digestion and helps to divert blood flow to important organs. LÄS MER
3. Mathematical Modelling of Insulin Signalling : Effects on Glucose Metabolism in Skeletal Muscle
Sammanfattning : The use of models to understand complex phenomena is indispensable to the scientific community. The advantage of a model is that it simplifies the phenomena under study. However, a model should be only as complex as required, no more, no less. LÄS MER
4. Systems-level investigation of the interaction between glucose metabolism and the Snf1/Mig1 signalling pathway
Sammanfattning : Saccharomyces cerevisiae Snf1 and its mammalian homolog, AMPK, are members of a protein kinase family present throughout the Eukaryotic kingdom. AMPK plays an essential role in different cellular processes and is involved in diseases such as diabetes, obesity and cancer. LÄS MER
5. Insulin signalling in human adipocytes : mechanisms of insulin resistance in type 2 diabetes
Sammanfattning : Prevalensen av fetma ökar drastiskt i stora delar av världen och utgör en stor riskfaktor för att utveckla insulinresistens och typ 2 diabetes. Fettväven kan bli mycket stor om för mycket energi tas upp av kroppen. LÄS MER