Sökning: "genomes"
Visar resultat 1 - 5 av 391 avhandlingar innehållade ordet genomes.
1. Methods for Analyzing Genomes
Sammanfattning : The human genome reference sequence has given us a two‐dimensional blueprint of our inherited code of life, but we need to employ modern‐day technology to expand our knowledge into a third dimension. Inter‐individual and intra‐individual variation has been shown to be larger than anticipated, and the mode of genetic regulation more complex. LÄS MER
2. Divergence, admixture and continuity in the human past : Demographic inference using ancient and modern genomes
Sammanfattning : Demographic forces shaping the genetic variation we observe today can include population divergences, admixture events and continuity through time. The advancement of high-throughput sequencing technologies, together with developments in molecular and bio-informatics methods, mean the number of ancient genomes available for inference has risen steeply. LÄS MER
3. Rates and patterns of molecular evolution in avian genomes
Sammanfattning : Evolution is the change in inherited characteristics of a population through subsequent generations. The interplay of several evolutionary mechanisms determines the rate at which this change occurs. LÄS MER
4. Neurospora tetrasperma from Natural Populations : Toward the Population Genomics of a Model Fungus
Sammanfattning : The study of DNA sequence variation is a powerful approach to study genome evolution, and to reconstruct evolutionary histories of species. In this thesis, I have studied genetic variation in the fungus Neurospora tetrasperma and other closely related Neurospora species. I have focused on N. LÄS MER
5. Computational exploration of cancer genomes
Sammanfattning : Cancer evolves due to changes in DNA that give a cell an advantage at the expense of the remaining organism. These alterations range from individual base substitutions to broad losses or duplications of chromosomal material. LÄS MER