Sökning: "genome mapping"
Visar resultat 16 - 20 av 162 avhandlingar innehållade orden genome mapping.
16. Genomic strategies towards the dissection of human complex disease
Sammanfattning : Complex diseases are caused by the activities of many genes acting in concert with environmental factors. A major challenge facing human genetic research is to unravel the genetic factors behind complex disorders. LÄS MER
17. Membrane protein topology : prediction, experimental mapping and genome-wide analysis
Sammanfattning : Membrane proteins constitute a large and important class of proteins. They are responsible for many crucial processes in living cells, and about 25% of all proteins encoded by a typical genome are predicted to be membrane proteins. Despite their importance, very few structures have been determined at atomic resolution. LÄS MER
18. Genome Evolution of Neurospora tetrasperma
Sammanfattning : In this thesis work, I have used a comparative genomics approach to study a fungal model organism, Neurospora tetrasperma. My specific focus has been on genomic introgression, intron evolution, chromosomal structural rearrangements and codon usage. LÄS MER
19. Gene mapping of atopic dermatitis
Sammanfattning : Atopic dermatitis is a hereditary, pruritic, inflammatory and chronic skin disease that typically presents in early childhood. It is often associated with other atopic manifestations, such as asthma, allergic rhinoconjunctivitis, and elevated total and/or allergen-specific serum lgE levels. LÄS MER
20. Novel methods for mapping genome organization and genome fragility in the 3D space of the nucleus
Sammanfattning : For over a century, scientists have been trying to understand how the DNA molecule that is so tightly packed in the micro space of the nucleus sustains critical cellular processes such as transcription, replication or the maintenance of genetic information. Despite the huge effort of researchers around the world, we know relatively little. LÄS MER
