Sökning: "genome mapping"

Visar resultat 1 - 5 av 118 avhandlingar innehållade orden genome mapping.

  1. 1. Genetic Mapping of Susceptibility Genes for Systemic Lupus Erythematosus

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Bo Johanneson; Uppsala universitet.; [2002]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Association analysis; Candidate gene; Complex disease; Genome scan; Linkage analysis; Mapping; Susceptibility genes; Systemic lupus erythematosus; Genetik; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik; medicinsk genetik; Medical Genetics;

    Sammanfattning : Systemic lupus erythematosus (SLE) is a complex autoimmune disease with unknown etiology. The aim of this thesis was to identify susceptibility regions through genetic mapping, using model-based linkage analysis on nuclear and extended SLE multicase families. LÄS MER

  2. 2. Genome mapping of the horse

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Gabriella Lindgren; Uppsala universitet.; [2001]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Horse; microsatellites; linkage analysis; FISH; Type I markers; BAc library; Y chromosome; Utvecklingsbiologi; NATURAL SCIENCES Biology Organism biology Developmental biology; NATURVETENSKAP Biologi Organismbiologi Utvecklingsbiologi; Evolutionary Genetics; evolutionär genetik;

    Sammanfattning : Our ability to map and sequence whole genomes is one of the most important developments in biological science. It will provide us with an unprecedented insight into the genetic background of phenotypic traits, such as disease resistance, reproduction and growth and also makes it feasible to study the processes of genome evolution. LÄS MER

  3. 3. Mapping the Rickettsia prowazekii genome

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Alireza Zomorodipour; Uppsala universitet.; [1998]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Rickettsia prowazekii is a member of alpha proteobacteria and the etiologic agent of epidemictyphus. Besides its pathogenicity as an obligate intracellular parasite it has been considered as amodel organism in a variety of studies.We have established a collection of overlapping clones, covering nearly the complete R.prowazekii genome. LÄS MER

  4. 4. Topics in Human Gene Mapping

    Detta är en avhandling från Mathematical Statistics, Centre for Mathematical Sciences, Lund University

    Författare :Azra Kurbasic; Lunds universitet.; Lund University.; [2007]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; actuarial mathematics; Statistik; programming; Statistics; Mathematics; Naturvetenskap; Natural science; hidden Markov model; linkage analysis; Human genome; disease gene; programmering; aktuariematematik; operationsanalys; operations research; Matematik;

    Sammanfattning : Popular Abstract in Swedish Att försöka lokalisera gener som ger upphov till sjukdomar är ingenting nytt. De första försöken gjordes redan i början av 1900-talet. Idén är ganska enkel. LÄS MER

  5. 5. Genome Variation in Human Populations Exploring the Effects of Demographic History and the Potential for Mapping of Complex Traits

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Åsa Johansson; Uppsala universitet.; [2006]
    Nyckelord :Genetics; genetics; evolution; microsatellie; SNP; selection; linkage disequilibrium; haplotype; Genetik;

    Sammanfattning : A major challenge in human genetics is to understand the genetic variation underlying common diseases. In this thesis, I focus on forces creating differences between individuals and genomic regions, methods for characterizing genomic variation, and the association between genomic and phenotypic variation. LÄS MER