Sökning: "flowcytometry"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet flowcytometry.

  1. 1. Clinical and Experimental Studies on Inflammatory Bowel Disease with special emphasis on Collagenous Colitis

    Författare :Michael Wagner; Marie Carlson; Maria Lampinen; Per Sangfelt; Erik Hertervig; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Collagenous colitis; inflammatory bowel disease; ulcerative colitis; Crohn´s disease; faecal markers; eosinophil; T-cells; ECP; EPX; MPO; calprotectin; flowcytometry; chromogranin A; chromogranin B; secretoneurin; budesonide; Gastroenterology; Gastroenterologi; Medicin; Medicine;

    Sammanfattning : This thesis describes studies in patients with inflammatory bowel disease (IBD) and collagenous colitis (CC). We investigated mucosal eosinophil and neutrophil granulocytes and T-cells involved in the inflammatory processes and aimed at determining whether these processes are reflected in the faecal (F) contents of specific proteins secreted by cells in the intestinal mucosa. LÄS MER

  3. 2. Proteinase 3 and Neutrophil Apoptosis in ANCA-Associated Systemic Vasculitis

    Författare :Mohamed AbdGawad; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wegener’s granulomatosis; anti-neutrophil cytoplasmic antibody ANCA . Proteinase 3 PR3 ; myeloperoxidase MPO . Flowcytometry FACS . Vasculitis.; microscopic polyangitis;

    Sammanfattning : ANCA-Associated Systemic Vasculitis (AASV) is characterized by leukocytoclasis- dying neutrophils surrounding small blood vessels. Previous studies have shown increased plasma PR3 and increased proportion of neutrophils expressing plasma membrane-associated PR3 (mPR3+). LÄS MER

  4. 3. Leukocyte rolling and firm adhesion in the microvasculature : functional significance for leukocyte recruitment in inflammation

    Författare :Xun Xie; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :adhesion molecules; blood flow; chemoattractants; endothelium; flowcytometry; fucoidin; heparin; inflammation; integrins; intravital microscopy; leukocyteadhesion; leukocyte extravasation; leukocyte rolling; meningitis; mesentery; microcirculation; ;

    Sammanfattning : Leukocyte recruitment to tissues is a key component in the inflammatory process. In order for circulating leukocytes to extravasate, they need to interact with vascular endothelium in several sequential steps. LÄS MER

  5. 4. Role of platelets and neutrophils in regulating trypsinogen activation and tissue damage in acute pancreatitis

    Författare :Aree Abdulla; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protease activation; adhesion molecule; chemokine; intravital flourecence microscopy; matrix metalloproteinase.;

    Sammanfattning : Acute pancreatitis is an inflammatory disease characterized by a diverse spectrum of clinical presentations ranging from a mild and self-limiting to a severe and systemic disorder. The relationship between inflammation and proteolytic activation in pancreatitis is an elusive issue. LÄS MER

  7. 5. A two-dimensional gel electrophoretic study of proteins in tumours of the lung and breast

    Författare :Bo Franzén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :gel electrophoresis; protein analysis; sample preparation; mammary tumour; lungcarcinomas; heterogeneity; diagnostic markers.;

    Sammanfattning : Defining differences in gene expression between benign and malignant cells is an important aspectof cancer research, and has been the object of a large number of studies. Such studies are aimed atdefining tumour markers to be used in prognostic studies, and to understand mechanisms leading touncontrolled growth and tumour metastasis. LÄS MER