Sökning: "fish protease"

Hittade 3 avhandlingar innehållade orden fish protease.

  1. 1. Haematopoietic Serine Proteases : A Cleavage Specificity Analysis

    Författare :Michael Thorpe; Lars Hellman; Urban Gullberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cell; cleavage specificity; phage display; chymase; serine protease; granzyme; fish protease;

    Sammanfattning : Mast cells are innate immune cells, historically involved in allergy responses involving IgE. Through this, they have earned a reputation as a fairly detrimental cell type. Their beneficial roles remain somewhat enigmatic although they clearly have the ability to modulate the immune system. LÄS MER

  3. 2. Hematopoietic Serine Proteases from the Mast Cell Chymase and Tryptase Loci - a Functional and Evolutionary Analysis

    Författare :Jenny Reimer; Lars Hellman; Gunnar Nilsson; Sara Wernersson; Göran Andersson; Uppsala universitet; []
    Nyckelord :Cell and molecular biology; immune system; mast cell; basophil; mast cell chymase locus; multigene tryptase locus; serine protease; evolution; Cell- och molekylärbiologi;

    Sammanfattning : Mast cells are key effector cells in allergic and inflammatory diseases. However, their primary role is most likely in host defence against parasitic and bacterial infections. Mast cells are a particularly rich source of serine proteases. LÄS MER

  4. 3. The role of angiomotin in endothelial cell motility and cell-cell junction formation

    Författare :Anders Bratt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Angiogenesis; cancer; angiostatin; angiomotin; cell motility cell-cell junction; tight junction; adherens junction;

    Sammanfattning : Clinical as well as pre-clinical data show that tumor growth can be restrained by inhibiting angiogenesis. We have been investigating the mechanism of action of angiostatin, an inhibitor of angiogenesis, in order to design novel therapies against cancer. LÄS MER