Sökning: "fibrillin-1"

Hittade 3 avhandlingar innehållade ordet fibrillin-1.

  1. 1. Studies on the extracellular matrix of the dysfunctional pelvic floor

    Författare :Marie Westergren Söderberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Pelvic floor; pelvic organ prolapse; stress urinary incontinence; extracellular matrix; collagen; SLRPs; decorin; lumican; fibromodulin; elastin associated proteins; fibrillin-1; fibulin-5; sex steroid hormone receptors; ER; PR; AR;

    Sammanfattning : Objective: Pelvic floor dysfunction cause impaired quality of life of many women and is one of the most common reasons for gynaecological surgery on benign indications. Little is known about the pelvic floor extracellular matrix as a pre-requisite for mechanical sustainability through vaginal delivery, age and hormonal changes. LÄS MER

  3. 2. EGF-like modules in blood coagulation proteins : Ca²+ binding, module interactions, structure and dynamics as studied by NMR spectroscopy

    Författare :Andreas Muranyi; Biofysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; residual dipolar couplings; protein S; factor VII; protein structure; calcium; blood coagulation; NMR spectroscopy; EGF modules; Physical chemistry; Fysikalisk kemi;

    Sammanfattning : Modules are independently folding protein domains defined on the gene level. The epidermal growth factor-like (EGF) modules are involved in protein-protein interactions and are found in numerous membrane proteins and extracellular proteins, including many proteins of the blood coagulation system. LÄS MER

  4. 3. Influence of genetics and mechanical properties on large arteries in man

    Författare :Rachel De Basso; Toste Länne; Martin Björck; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Arterial pathology is the major contributor to cardiovascular diseases and mortality. The mechanical properties of arteries are independent factors for cardiovascular disease and mortality, where genetics influence the structure of the arterial wall, which may result in change in arterial stiffness. LÄS MER