Sökning: "female genital tract immunity"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden female genital tract immunity.

  1. 1. Development of novel immunization approaches to generate immunity in the female genital tract with special reference to genital herpes

    Författare :Sara Tengvall; Göteborgs universitet; []
    Nyckelord :female genital tract immunity; genital herpes; mucosal adjuvant; TLR; MyD88; CpG ODN;

    Sammanfattning : Development of mucosal vaccines for inducing immunity in the female reproductive tract would have profound implications for the prevention of sexually transmitted diseases. Despite numerous efforts, no such vaccines are currently available for human use. LÄS MER

  3. 2. Mucosal adjuvants and their mode of action in the female genital tract

    Författare :Madelene Lindqvist; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunology; mucosal adjuvants; genital tract; vaccine; HSV-2; mouse; alpha-galactosylceramid; CpG ODN; proteoliposome-derived cochleate; inflammation; bioinformatics;

    Sammanfattning : Sexually transmitted infections (STIs) cause a socioeconomic burden, morbidity and even mortality in a large part of the human population all over the world today. One of the most common genital ulcerative diseases is caused by herpes simplex virus type 2 with over 536 million people infected world-wide. LÄS MER

  4. 3. Biology of HIV transmission and antiviral mucosal immunity in the female genital tract

    Författare :Pauline Levinson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human immunodeficiency virus (HIV) is primarily transmitted through heterosexual intercourse and women in Sub-Saharan Africa are disproportionately affected. Correlates of protective immunity and mucosal factors influencing sexual HIV transmission need to be identified as they may serve as critical targets for HIV intervention. LÄS MER

  5. 4. Innate immune factors in recurrent and persistent infections of the lower female genital tract

    Författare :Cathrin Alvendal; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :C. albicans;

    Sammanfattning : Background: Infections of the female genital tract are common and have severe impact on the quality of life and sexual health of affected women. The innate immune system is crucial and is involved in the defense of infections. LÄS MER

  7. 5. Human vaginal epithelial immunity and influences of hormonal contraceptive usage

    Författare :Anna Ildgruben; Nils Lycke; Umeå universitet; []
    Nyckelord :human vaginal epithelium; hormonal contraceptives; epithelial thickness; intraepithelial immune cells; steroid receptors; steroid hormones; defensins; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : The vagina is the port of entry for sexually transmitted diseases in women. Its epithelium constitutes the luminal border, thus comprising an important defence barrier. LÄS MER