Sökning: "endothelial activation"

Visar resultat 1 - 5 av 279 avhandlingar innehållade orden endothelial activation.

  1. 1. Endothelial activation and inflammation in the tumor microenvironment

    Författare :Hua Huang; Anna Dimberg; William C. Aird; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumor angiogenesis; endothelial activation; leukocyte recruitment; VEGF-A; αB-crystallin; ELTD1;

    Sammanfattning : Tumors are composed not only of malignant cells, but also of various types of normal cells, including vascular cells and infiltrating immune cells, which drive tumor development and progression. The tumor vasculature is abnormal and dysfunctional due to sustained tumor angiogenesis driven by high levels of pro-angiogenic factors. LÄS MER

  3. 2. Vascular Interactions in Innate Immunity and Immunothrombosis: : Models of Endothelial Protection

    Författare :Sofia Nordling; Peetra Magnusson; Paul Kubes; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endothelial cells; Thrombosis; Innate immunity; Immunothrombosis; Thromboinflammation; Immunologi; Immunology;

    Sammanfattning : The phenomenon known as immunothrombosis has garnered increased attention over the last few years. Much work has been done to characterize the cross talk between hemostasis and the innate immune system. LÄS MER

  4. 3. On the role of mast cells in chemokine-induced leukocyte recruitment

    Författare :Yusheng Wang; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chemokines; mast cells; TNF-alpha; dexamethasone; P-selectin; E-selectin; activation; Medicine human and vertebrates ; endothelial cells; adhesion; Neutrophil; Medicin människa och djur ; recruitment;

    Sammanfattning : Leukocyte recruitment is considered to playa key role in numerous inflammatory diseases. Tissue accumulation of Jeukocytes is a multi-steps process comprising rolling, adhesion and transmigration. LÄS MER

  5. 4. Artificial blood vessels - Studies on endothelial cell and blood interactions with bacterial cellulose

    Författare :Helen Fink; Göteborgs universitet; []
    Nyckelord :bacterial cellulose; endothelial cells; thrombogenicity; xyloglucan; contact activation; imaging of coagulation; vascular grafts; RGD; cell adhesion; bioreactor; xyloglucan;

    Sammanfattning : Cardiovascular diseases are still the number one cause of death or invalidity in the western world today. Atherosclerotic plaques and restenosis can result in severe occlusions of peripheral and coronary arteries. Treatment depends on the severity of the disease and includes drug therapy and bypass surgery. LÄS MER

  7. 5. Neutrophil and endothelial cell-mediated inflammation in abdominal sepsis

    Författare :Zhiyi Ding; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; lung; neutrophil; endothelial cell; neutrophil extracellular traps; inflammation; capillary; post capillary venules; cytoskeleton; RNAseq;

    Sammanfattning : Sepsis is defined as a life-threatening condition caused by a dysregulated host response to infection. Neutrophils are themost abundant innate immune cells of the body and play a key role in septic pathogenesis. LÄS MER