Sökning: "enantiomer separation"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden enantiomer separation.

  1. 1. Sensitivity and selectivity studies in capillary electrophoresis

    Författare :Maria Petersson; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; peptides; dansyl amino acids; imaging detection; cyclodextrins; enantiomer separation; acoustic levitation; solid-phase extraction; preconcentration; capillary electrophoresis; micellar electrokinetic chromatography; drugs; Analytical chemistry; Analytisk kemi;

    Sammanfattning : Capillary electrophoresis is characterised by high separation efficiency, applicability to a wide range of compounds, small sample and solvent consumption and simple instrumentation. To improve sensitivity using on-line absorbance detectors, which are hampered by the short optical path length, sample volumes in the microlitre range were concentrated to nanolitre volumes either off-line or on-line. LÄS MER

  3. 2. New applications and developments of field-asymmetric ion mobility spectrometry - mass spectrometry (FAIMS-MS)

    Författare :Axel Mie; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; triazine; enantiomer; ion focusing; ion mobility; FAIMS; DMS; axial ion inlet;

    Sammanfattning : Field asymmetric ion mobility spectrometry (FAIMS), also commonly termed differential mobility spectrometry (DMS), is a gas-phase ion separation technology. FAIMS exploits differences in high-electric-field to low-electric-field ion mobility ratios to discriminate between ion species. LÄS MER

  4. 3. Molecularly Imprinted Matrices for Electrochromatography

    Författare :Leif Schweitz; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemical technology and engineering; capillary electrophoresis; enantiomer; film coating; microparticle; continuous bed; monolith; molecular imprinting; capillary electrochromatography; Kemiteknik och kemisk teknologi; Analytical chemistry; Analytisk kemi;

    Sammanfattning : This thesis deals with the combination of electrochromatography and molecular imprinting technology. Electrochromatography is characterised by high separation efficiency, simple instrumentation, and minute consumption of sample. LÄS MER

  5. 4. Aspects of Porous Graphitic Carbon as Packing Material in Capillary Liquid Chromatography

    Författare :Anna Törnkvist; Wolfgang Lindner; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; PGC; porous graphitic carbon; stationary phase; packing material; LC; liquid chromatography; miniaturized; chiral; enantiomer; ESI; electrospray ionization; mass spectrometry; polar compounds; L-DOPA; dopamine; biological samples; biological matrix; Analytisk kemi; PGC; poröst grafitiserat kol; stationärfas; packningsmaterial; LC; vätskekromatografi; miniatyriserade system; kiral; enantiomer; ESI; electrospray jonisation; mass spektrometri; polära föreningar; L-DOPA; dopmamine; biologiska prover; biologisk matris; Analytical chemistry; Analytisk kemi; Analytical Chemistry; Analytisk kemi;

    Sammanfattning : In this thesis, porous graphitic carbon (PGC) has been used as packing material in packed capillary liquid chromatography. The unique chromatographic properties of PGC has been studied in some detail and applied to different analytical challenges using both electrospray ionization-mass spectrometry (ESI-MS) and ultra violet (UV) absorbance detection. LÄS MER

  7. 5. Introducing weak affinity chromatography to drug discovery with focus on fragment screening

    Författare :Minh-Dao Duong-Thi; Sten Ohlson; Brian Dymock; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; affinity LC-MS; fragment-based drug discovery; fragment screening; high throughput; mass spectrometry; stereoisomer; enantiomer; thrombin; weak affinity chromatography; WAC; WAC-MS.; Biomedical Sciences; Biomedicinsk vetenskap; Biokemi; Biochemistry;

    Sammanfattning : Fragment-based drug discovery is an emerging process that has gained popularity in recent years. The process starts from small molecules called fragments. One major step in fragment-based drug discovery is fragment screening, which is a strategy to screen libraries of small molecules to find hits. LÄS MER