Sökning: "editing"

Visar resultat 1 - 5 av 141 avhandlingar innehållade ordet editing.

1. 1. Redigering och skuld : Ett kognitivt perspektiv på redigeringensfunktioner i ansvarsutkrävande tv-reportage

   Författare :Piotr Urniaz; Stefan Sjöström; Göran Ericsson; Umeå universitet; []
   Nyckelord :HUMANIORA; HUMANITIES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; TV journalism; attribution of guilt; mental models; Jürgen Habermas; Formal Pragmatics; visual communication; communicative ethics; media literacy; cognition; the viewer; investigative journalism; media accountability; political scandals; critical realism; documentary film; Tv-journalistik; granskande journalistik; redigering; dokumentärfilm; reception; kommunikativ etik; Jürgen Habermas; audiovisuell kommunikation; argumentation; skuld; skuldattribuering; ansvarsutkrävande; medieskandaler; formalpragmatik; manipulation; komposition; medie- och kommunikationsvetenskap; media and communication studies;

   Sammanfattning : Abstract: During the past decade, media researchers have intensified the study of media scandals and the role of journalism as an institution that holds social actors responsible for malfeasance and wrongdoings. On a micro level of analysis, the main attention has beendirected towards the journalistic interview and its use to promote the impression of guilt and journalistic neutrality. LÄS MER

3. 2. Regulation of RNA Editing : The impact of inosine on the neuronal transcriptome

   Författare :Mikaela Behm; Marie Öhman; André Gerber; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA editing; ADAR; miRNA; Neuron; Brain development; Synapse; Molecular Biology; molekylärbiologi;

   Sammanfattning : The transcriptome of the mammalian brain is extensively modified by adenosine to inosine (A-to-I) nucleotide conversion by two adenosine deaminases (ADAR1 and ADAR2). As adenosine and inosine have different base pairing properties, A-to-I RNA editing shapes the functional output of both coding and non-coding RNAs (ncRNAs) in the brain. LÄS MER

4. 3. The diverse functions of the ADAR enzymes : Editing and editing-independent effects on gene expression

   Författare :Victor Karlström; Neus Visa; Ayelet Lamm; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA editing; ADAR; Alternative splicing; miRNA processing; neuronal differentiaton; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : The adenosine deaminase acting on RNA (ADAR) family of enzymes consists of three members (ADAR1-3). These enzymes are responsible for the deamination of adenosine into inosine in double-stranded RNA, one of the most common RNA modifications in mammals. LÄS MER

5. 4. A-to-I RNA editing : Function and consequences during brain development

   Författare :Ylva Ekdahl; Marie Öhman; Kazuko Nishikura; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA editing; miRNAs; Brain development; Molecular Biology; molekylärbiologi;

   Sammanfattning : The aim of my thesis has been to study how A-to-I RNA editing of miRNAs is regulated during brain development and the biological function of these editing events.Using high throughput RNA sequencing, we performed an unbiased search for edited, mature miRNAs in total mouse brain tissue from three developmental stages. LÄS MER

7. 5. Understanding Cancer Mutations by Genome Editing

   Författare :Muhammad Akhtar Ali; Tobias Associate Professor; Thierry Soussi; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genome editing; rAAV; ZBED6; DIP2C; KRAS; BRAF; colorectal cancer; tumor driver genes; cancer pathways;

   Sammanfattning : Mutational analyses of cancer genomes have identified novel candidate cancer genes with hitherto unknown function in cancer. To enable phenotyping of mutations in such genes, we have developed a scalable technology for gene knock-in and knock-out in human somatic cells based on recombination-mediated construct generation and a computational tool to design gene targeting constructs. LÄS MER