Sökning: "early B-cell factor 1 EBF1"
Hittade 4 avhandlingar innehållade orden early B-cell factor 1 EBF1.
1. To be or not to be, unraveling molecular mechanisms for lineage decisions in developing blood cells
Sammanfattning : All hematopoietic cells originate from hematopoietic stem cells (HSC) residing in the BM. The process of differentiation, through which HSCs generate progenitors and subsequently mature blood cells has been extensively studied but many of the regulatory mechanisms involved remains elusive. LÄS MER
2. The regulatory role of microRNA in human adipocytes and their link to insulin resistance
Sammanfattning : White adipose tissue (WAT) is a highly plastic organ which secretes a large number of peptide factors termed adipokines. Increased caloric intake increases WAT mass which results in marked alterations in the secretory pattern. This may be mediated via both transcriptional and post-transcriptional mechanisms. LÄS MER
3. Identification of novel factors regulating human adipocyte function and their link to metabolic health
Sammanfattning : The white adipose tissue (WAT) regulates energy homeostasis by storing and releasing energy in the form of fat as well as functioning as an endocrine organ secreting a myriad of different peptides. The heterogeneous WAT consists of various cell types including the lipid-storing cells termed adipocytes. LÄS MER
4. Pathophysiological mechanisms and clinical manifestations in primary Sjögren’s syndrome and Systemic lupus erythematosus (SLE)
Sammanfattning : Primary Sjögren’s syndrome (pSS) is a systemic inflammatory autoimmune condition. The etiology of pSS is mainly unknown, but it has been suggested that environmental factors trigger an immune response in genetically susceptible individuals. LÄS MER