Sökning: "drugs increase"

Visar resultat 1 - 5 av 604 avhandlingar innehållade orden drugs increase.

1. 1. Pharmacoepidemiologic studies on cardiovascular drugs - with special reference to the effectiveness and safety of blood pressure lowering drugs

   Författare :Juan Merlo; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences; samhällsmedicin; Socialmedicin; cardiovascular epidemiology; Pharmacoepidemiology; blood pressure; hypertension; cardiovascular drugs; antihypertensive drugs; lipid lowering drugs; nitrates; effectiveness; safety; ecologic studies; Social medicine; cohort studies; farmakognosi; farmaci; toxikologi;

   Sammanfattning : Background: Ischaemic heart disease (IHD) and stroke are the main causes of morbidity and mortality in developed countries and hence constitute a large public health problem. Cardiovascular drugs are used in an effort to prevent (e. g. blood pressure lowering drugs (BPLD) and lipid lowering drugs) and palliate (e. LÄS MER

3. 2. Fish on drugs : behaviour modifying contaminants in aquatic ecosystems

   Författare :Annelie Lagesson; Jonatan Klaminder; Tomas Brodin; Kathryn Arnold; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Aquatic ecosystems; Behavioural effects; Ecotoxicology; Endocrine disruptors; Pharmaceuticals; Interaction effects; ekotoxikologi; Ecotoxicology;

   Sammanfattning : Contamination of surface waters is a worldwide problem. One group of emerging contaminants that reach aquatic ecosystems via sewage treatment plant effluents and agricultural run-offs is pharmaceuticals. LÄS MER

4. 3. China's Creation of Biopharmaceutical Drugs : Combining Political Steering, Military Research, and Transnational Networking

   Författare :Åse Linné; Alexandra Waluszewski; Enrico Baraldi; David Ford; Uppsala universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; innovation; biotechnology; China; resource interfaces; commerciali-zation; Chinese government; command network economy; biopharmaceutical drugs; military research;

   Sammanfattning : Not only the Western world is focused on creating new innovations based on scientific discoveries; this is also the case in China where discoveries in biotechnology science are aimed at creating new biopharmaceutical drugs in order to create a future biotechnology industry and in the end generate economic growth. The focus to invest in high-tech industries such as biotechnology can be traced to the “open-door policy” issued in 1978 with the aim to modernize China and transform China into a “socialistic market economy. LÄS MER

5. 4. Molecular Profiling and Imaging of Peptides, Proteins and Drugs in Biological Tissue using Mass Spectrometry

   Författare :Anna Nilsson; Per E. Andrén; Garry Corthals; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peptidomics; mass spectrometry; liquid chromatography; MALDI imaging; neuropeptides; drugs; brain; Pharmacology; Farmakologi;

   Sammanfattning : Biological functions within cells and organisms are mainly carried out by the translational products; proteins and peptides. The analysis and characterization of these biomolecules are of great importance for the progress in disease research and biomarker and drug discovery. LÄS MER

7. 5. Intestinal absorption of drugs : The impact of regional permeability, nanoparticles, and absorption-modifying excipients

   Författare :Carl Roos; Hans Lennernäs; Erik Sjögren; Martin Brandl; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Permeability; intestinal absorption; regional permeability; nanoparticles; nanosuspensions; absorption-modifying excipients; AMEs; Biofarmaci; Biopharmaceutics;

   Sammanfattning : For successful delivery of orally given drug products, the drug compounds must have adequate solubility and permeability in the human gastrointestinal tract. The permeability of a compound is determined by its size and lipophilicity, and is usually evaluated in various pre-clinical models, including rat models. LÄS MER