Sökning: "drug normalization"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden drug normalization.

  1. 1. Socially Integrated Drug Users : Between Deviance and Normality

    Författare :Sharon Rødner Sznitman; Robin Room; Adrienne Sörbom; Geoffrey Hunt; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Socially integrated drug users; Sweden; Switzerland; drug normalization; mixed methods; Sociology; Sociologi; Sociology; sociologi;

    Sammanfattning : The purpose of this thesis is to improve our knowledge of substance users in the normal population. The main concern is with how the meaning of drug use is constructed. To answer this, the thesis draws on different theoretical principles and mixed methods design. The thesis is made up of four sub-studies, with interconnected foci. LÄS MER

  3. 2. Transcriptomics and Proteomics Applied to Developmental Toxicology

    Författare :Kim Kultima; Lennart Dencker; Timothy Gant; Uppsala universitet; []
    Nyckelord :Toxicology; 2D-DIGE; Valproic acid; PBDE-99; Flame retardant; Neural tube defects; Microarray; In vivo; In vitro; Biomarker; Brain growth spurt; Normalization; Mouse embryo; Toxicogenomics; Toxikologi;

    Sammanfattning : Developmental toxicology is an important part of preclinical drug toxicology as well as environmental toxicology. Assessing reproductive and developmental toxicity is especially expensive and time demanding, since at least two generations of animals are needed in the tests. LÄS MER

  4. 3. Essays on spatial point processes and bioinformatics

    Författare :Jessica Fahlén; Patrik Rydén; Xavier de Luna; Yudi Pawitan; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Coverage process; vacancy; microarray; pre-processing; sensitivity; bias; dye-normalization; FFPE; storage time effects; Statistics; Statistik; Statistics; statistik;

    Sammanfattning : This thesis consists of two separate parts. The first part consists of one paper and considers problems concerning spatial point processes and the second part includes three papers in the field of bioinformatics. LÄS MER

  5. 4. Levodopa- and Neuroleptic-Induced Dyskinesias : Studies on Pharmacological Modification and Processing of Opioid Neuropeptides

    Författare :Rebecka Klintenberg; Alan Crossman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biological research on drug dependence; Opioid peptides; dyskinesia; Parkinson s disease; mass spectrometry; metabolism; Biologisk beroendeforskning; Biological research on drug dependence; Biologisk beroendeforskning; biologisk beroendeforskning; Biological Research on Drug Dependence;

    Sammanfattning : Dyskinesias or abnormal involuntary movements are a debilitating complication of long-term levodopa treatment of Parkinson’s disease (PD) that is widely experienced and may compromise the efficacy of the drug therapy. Tardive dyskinesia is another important adverse effect seen with antipsychotic drug treatment. LÄS MER

  7. 5. Synaptic plasticity in drug abuse disorders : studies of the human post-mortem brain

    Författare :Anna Ökvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Drug addiction is a chronic disorder characterized by craving and compulsive drug use despite adverse consequences and high rates of relapse during periods of abstinence. Therapeutic interventions for most addiction disorders are limited today, partly because the underlying neurobiology is still unknown. LÄS MER