Sökning: "drosophila differentiation"

Visar resultat 1 - 5 av 36 avhandlingar innehållade orden drosophila differentiation.

  1. 1. Revisiting cell specification and differentiation in the Drosophila airways, an insect organ homologous to our lung and blood vessels

    Författare :Ryo Matsuda; Christos Samakovlis; Payre Francois; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cell differentiation; airways; Drosophila; cell signaling; transcription factors; utvecklingsbiologi; Developmental Biology;

    Sammanfattning : Oxygen is essential for life. Aquatic ancestral animal species are thought to have independently terrestrialized and invented distinct strategies for efficient oxygen supply. The respiratory system of vertebrates like us is composed of lungs connected to the vasculature while insects have a single system delivering air directly to internal tissues. LÄS MER

  3. 2. Regulators of chromatin and transcription in Drosophila

    Författare :Filip Crona; Mattias Mannervik; Fernando Azorin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Transcription; chromatin; co-regulators; CBP; lysine demethylase; KDM4A; Brakeless; Drosophila; utvecklingsbiologi; Developmental Biology;

    Sammanfattning : Development of multicellular organisms is achieved by organized temporal and spatial patterns of gene expression leading to cell differentiation. Chromatin regulators control how the DNA is utilized by altering access of proteins to DNA and thereby function as co-factors in transcription. LÄS MER

  4. 3. Molecular characterization of the Drosophila responses towards nematodes

    Författare :Md. Badrul Arefin; Ulrich Theopold; Ioannis Eleftherianos; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Drosophila; nematodes; infection; danger situations; immune response; coagulation; apoptosis; nitric oxide; leukemia; Molecular Biology; molekylärbiologi;

    Sammanfattning : A sophisticated evolutionary conserved innate immune system has evolved in insects to fight pathogens and to restrict damage in harmful (danger) situations including cancer. A significant amount of knowledge about different infection models in Drosophila has been generated in past decades, which revealed functional resemblances and implications for vertebrate systems. LÄS MER

  5. 4. Functions of Transcriptional Co-regulators in Drosophila development

    Författare :Tobias Lilja; Mattias Mannervik; Ze'ev Paroush; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Transcription; Co-regulator; Development; Drosophila; Developmental biology; Utvecklingsbiologi; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Sammanfattning : During Drosophila development, regulation of gene expression through interplay between transcriptional activators and repressors is generating complex patterns of gene expression that leads to cell differentiation. For proper control of transcription, transcription factors bind to DNA at control regions, so called Cis Regulatory Modules (CRM). LÄS MER

  7. 5. Genetic dissection of tubulogenesis in the Drosophila trachea

    Författare :Johanna Hemphälä; Christos Samakovlis; Reinhard Schuh; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; trachea; transposon mutagenesis screen; fusion; Dpp; Delta; tubular dimensions; Grainyhead; Krotzkopf verkehrt; intralumenal matrix; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : The formation of branched tubular organs, such as the mammalian lung kidney and vascular system, is an essential process in animal development. The Drosophila tracheal (respiratory) system provides a genetic model system to study the highly ordered process of branch outgrowth and fusion required to form continuous tubular networks. LÄS MER