Sökning: "developmental exposure"

Visar resultat 1 - 5 av 124 avhandlingar innehållade orden developmental exposure.

  1. 1. Developmental exposure to mixtures of environmental pollutants : Studies on metabolism, developmental processes, and reproductive organs in zebrafish and chicken embryos

    Författare :Anna Mentor; Maria Jönsson; Patrick Babin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mixtures; Developmental toxicology; Endocrine disrupting chemicals; Metabolism; Feminization; Zebrafish; Chicken embryo; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi;

    Sammanfattning : Humans and wildlife are continuously exposed to mixtures of environmental pollutants. Mixture toxicity can be challenging to predict due to interactions between chemicals and thus whole-mixture approaches are crucial in toxicology. LÄS MER

  3. 2. Environmental pollutants and the reproductive system in birds : Developmental effects of estrogenic compounds

    Författare :Cecilia Berg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Avian embryo; test system; xeno-estrogen; endocrine disruption; reproductive organ differentiation; oviduct; testis; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Ecotoxicology; ekotoxikologi;

    Sammanfattning : A number of environmental pollutants have been shown to mimick the action of the female sex hormone estrogen and are, therefore, suspected to be responsible for reproductive abnormalities seen in wildlife. Test systems which can be used in hazard and risk assessment of chemicals with estrogenic effects are consequently needed. LÄS MER

  4. 3. Developmental Neurotoxicity of Environmental Pollutants : Effects on neuronal protein markers after neonatal exposure

    Författare :Iwa Lee; Henrik Viberg; Elena Jazin; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental neurotoxicity; Neonatal exposure; Protein markers; Environmental pollutants; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Sammanfattning : This thesis focused on investigations of the developmental neurotoxic effects of bisphenol A (BPA) or perfluorohexane sulfonate (PFHxS), after a single neonatal exposure, during a critical period of the brain development in mice.BPA is a well-known industrial chemical used in the production of polymer products and PFHxS is used as an industrial additive as a surfactant. LÄS MER

  5. 4. Cellular transport and secretion of the cyanobacterial neurotoxin BMAA into milk and egg : Implications for developmental neurotoxicity

    Författare :Marie Andersson; Ingvar Brandt; Cynthia de Wit; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; BMAA; beta-N-methylamino-L-alanine; milk; secretion; amino acid transporter; autoradiography; metabolism; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Sammanfattning : The cyanobacterial amino acid β-N-methylamino-L-alanine (BMAA) is a neurotoxin implicated in the etiology of neurodegenerative diseases. Cyanobacteria are cosmopolitan organisms present in various environments. LÄS MER

  7. 5. Evolutionary ecology of ultraviolet-B radiation stress tolerance in amphibians

    Författare :Maarit Pahkala; Trevor Beebee; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; amphibians; anomalies; embryonic development; geographic variation; growth; Rana arvalis; Rana temporaria; survival; UV-B radiation; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; populationsbiologi; Population Biology;

    Sammanfattning : During the last decades many amphibian species and populations have experienced declines and extinctions in different parts of the world. Anthropogenic activities are believed to account for these declines, and one of the hypothesized causes has been the increased level of ultraviolet-B (UV-B) radiation due to depletion of the stratospheric ozone layer. LÄS MER