Sökning: "destruction"

Visar resultat 1 - 5 av 459 avhandlingar innehållade ordet destruction.

  1. 1. Controlling Weapons of Mass Destruction : An Evaluation of International Security Regime Significance

    Författare :Charles F. Parker; Michael Zürn; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Political science; Regimes; security; international cooperation; compliance; weapons of mass destruction; arms control; non-proliferation; nuclear weapons; biological weapons; chemical weapons; NPT; BTWC; CWC; CTBT; Statsvetenskap; Political science; Statsvetenskap; statskunskap; Political Science;

    Sammanfattning : This dissertation conducts an in-depth examination of the three weapons of mass destruction control regimes: the nuclear non-proliferation regime, the biological weapons control regime, and the chemical weapons control regime (NBC weapon control regimes). By examining a number of key indicators, this study investigates the specific ways each regime makes or does not make a difference in its respective issue area. LÄS MER

  3. 2. The Path to Destruction : Understanding the mechanism and regulation of proteasomal degradation

    Författare :Anne Beskow; Patrick Young; Ylva Engström; Bernat Crosas; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Proteasome; ubiquitin; p97; Cnc-C; transcription factors; Nrf1; Nrf2; Molecular Biology; molekylärbiologi;

    Sammanfattning : A majority of intracellular proteins are degraded by the ubiquitin proteasome system (UPS). In this thesis, both the mechanism of the degradation and the regulation of UPS have been investigated. The importance of the p97 ATPase for proteasomal degradation of cytosolic substrates was examined. LÄS MER

  4. 3. Modeling Genome Evolution : Creation, Change and Destruction

    Författare :Mats Pettersson; Otto Berg; Paul Sniegowski; Uppsala universitet; []
    Nyckelord :Molecular biology; Theotretical biology; Population genetics; Stochastic modeling; Genome evolution; Molekylärbiologi;

    Sammanfattning : Historically, evolution has been studied either by looking at morphological traits in living organisms and the fossil record, or by using bioinformatics and comparative genomics. While highly useful for deducing evolutionary history, these approaches are not particularly well suited for studying the mechanisms of evolution. LÄS MER

  5. 4. Preserving Impermanence : The Creation of Heritage in Vientiane, Laos

    Författare :Anna Karlström; Paul Sinclair; Frands Herschend; Beverley Butler; Uppsala universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Vientiane; Laos; heritage; impermanence; preservation; restoration; destruction; immateriality; materiality; narrativity; Buddhism; animism; Archaeology subjects; Arkeologiämnen; arkeologi; Archaeology; kulturantropologi; Cultural Anthropology; Ethnology; etnologi; historia; History;

    Sammanfattning : This thesis is about the heritage in Vientiane. In an attempt to go beyond a more traditional descriptive approach, the study aims at bringing forward a discussion about the definition, or rather the multiplicity of definitions, of the concept of heritage as such. LÄS MER

  7. 5. Cartilage destruction - Release of type IX collagen in joint disease

    Författare :Mikael Danfelter; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cartilage destruction; matrix metalloproteinase 13; ECM; assay; neoepitope; NC4 domain; Type IX collagen; fragment;

    Sammanfattning : Cartilage is of vital importance for the function of joints. It is characterized by a prominent extracellular matrix (ECM) that is produced and maintained by relatively few cells of one type, the chondrocyte. LÄS MER