Sökning: "dermatoses"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet dermatoses.
1. Malassezia-related diseases
Sammanfattning : The purpose of this thesis is to investigate whether the new taxonomy of Malassezia may have important clinical implications. In particular, the studies look at pityriasis versicolor and other dermatological disorders associated with Malassezia yeasts to see whether there is a clear association between the yeast species and body site colonized and/or disease state. LÄS MER
2. Methylisothiazolinones. Diagnosis and prevention of allergic contact dermatitis
Sammanfattning : Preservatives are biologically active substances which are required in water-based products/systems to prevent growth of micro-organisms. Kathon® CG (K-CG), one of several preservatives based on 5-chloro-2-methyl-4-isothiazolinon-3-one (MCI) and 2-methyl-4-isothiazolin-3-one (MI) has been shown to be a common sensitizer in dermatitis patients. LÄS MER
3. Vitamin A and ß-carotene metabolism and effects of UV irradiation in human keratinocytes and melanocytes
Sammanfattning : Retinoids (vitamin A and its derivatives) are modulators of proliferation and differentiation. Both retinol (ROH) and its metabolite 3,4-didehydroretinol (ddROH) can be converted to retinoic acid (RA) and 3,4-didehydroretinoic acid (ddRA), ligands for the nuclear receptors, which induce gene transcriptions. LÄS MER
4. Resident T cells steer tissue responses in human skin
Sammanfattning : The human skin constitutes a biological barrier against threats to the body from the surrounding environment. Tissue-resident memory cells (TRM) reside in the skin and provide local memory of previous encounters with microbes and pathogens, are poised to promptly eliminating infected cells and elicit tissue-wide defense state. LÄS MER
5. Harnessing the immunoregulatory capacity of single-stranded oligonucleotides to modulate innate immunity
Sammanfattning : As the first line of defense, the innate immune system is exceptionally efficacious against invading pathogens but must be tightly regulated to avoid immune-related pathogenesis. Accordingly, the innate immune system recognizes highly conserved components associated with infections and damaged cells using a limited number of pattern-recognition receptors (PRRs), which are differentially expressed across cell types. LÄS MER