Sökning: "dermal"

Visar resultat 1 - 5 av 131 avhandlingar innehållade ordet dermal.

  1. 1. Dermal cell trafficking : from microscopy to microdialysis

    Författare :Florence Sjögren; Magnus Lindberg; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The term dermal cell trafficking has been used to describe the dynamic nature of cell movement in the dermis reflecting the skin's role as an immunological organ. A light microscopic experimental model for qualitative and quantitative counting of the dermal inflammatory cell infiltrate in allergic, acute irritant and cumulative irritant contact reactions has been developed In human studies use of microdialysis technique has enabled observation of biochemical events in the skin, in vivo over a period of time. LÄS MER

  2. 2. Differentiation of Human Dermal Fibroblasts : a New Tool in Vascular Tissue Engineering

    Författare :Lisa Karlsson; Gunnar Kratz; Magnus Grenegård; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Tissue engineering is an expanding field, which focuses on the development of func-tional substitutes for damaged tissues. A limitation in this field is difficulties with obtaining autologous cells. Recent research has shown the presence of cells with multilineage-potential within the connective stroma of the skin. LÄS MER

  3. 3. Regulation of fibroblast activity by keratinocytes, TGF-β and IL-1α : studies in two- and three dimensional in vitro models

    Författare :Anita Koskela von Sydow; Mikael Ivarsson; Torbjörn Bengtsson; Hans Törmä; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fibroblast; Keratinocyte; TGF-β; IL-1α; coculture; fibrosis CTGF CNN 2; dermal; organotypic culture;

    Sammanfattning : Dysregulated wound healing is commonly associated with excessive fibrosis. Connective tissue growth factor (CTGF/CCN2) is characteristically overexpressed in fibrotic diseases and stimulated by transforming growth factor-β (TGF-β) in dermal fibroblasts. Reepithelialisation and epidermal wound coverage counteract excessive scar formation. LÄS MER

  4. 4. Differentiation of Human Dermal Fibroblasts and Applications in Tissue Engineering

    Författare :Pehr Sommar; Gunnar Kratz; Thomas Hansson; Anders Lindahl; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tissue Engineering; Human Dermal Fibroblasts; Differentiation; Adipogenesis; Chondrogenesis; Endotheliogenesis; Osteogenesis; Plastic surgery; Plastikkirurgi;

    Sammanfattning : Tissue engineering applies principles of biology and engineering to the development of functional substitutes for damaged or lost tissues. Tools for the neo-generation of tissue in tissue engineering research include cells, biomaterials and soluble factors. LÄS MER

  5. 5. Human Dermal Fibroblasts in Tissue Engineering

    Författare :Johan Junker; Gunnar Kratz; Hans Johnson; Anders Lindahl; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The loss or failure of tissues and/or organs is one of the most frequent problems in modern healthcare. The field of tissue engineering applies the principles of biology and engineering in order to develop functional substitutes for damaged tissues. LÄS MER