Sökning: "denaturation"

Visar resultat 1 - 5 av 67 avhandlingar innehållade ordet denaturation.

  1. 1. On the mechanism of Urea-induced protein denaturation

    Författare :Matteus Lindgren; Per-Olof Westlund; Arnold Maliniak; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemical denaturation; Protein unfolding; urea; MD simulations; NMR spectroscopy; Biophysical chemistry; Biofysikalisk kemi; fysikalisk kemi; Physical Chemistry;

    Sammanfattning : It is well known that folded proteins in water are destabilized by the addition of urea. When a protein loses its ability to perform its biological activity due to a change in its structure, it is said to denaturate. LÄS MER

  3. 2. Exploring the functionality of coconut proteins

    Författare :Borges Chambale; Livsmedelsteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Coconut; coconut milk; extraction; proteins; emulsions; functional properties; denaturation; gels; yield stress; glass structure;

    Sammanfattning : At present, coconut proteins are discarded as a waste product by the coconut oil industry. If the range of applications of coconut proteins is to be expanded, their potential functionalities should be investigated. Emulsions and gels are of the greatest interest in food industry. LÄS MER

  4. 3. Biophysical Studies of Apolipoprotein A-IM and a Partitioning study

    Författare :Malin Suurkuusk; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Apolipoprotein A-IMilano; Apolipoprotein A-I; Lipoprotein; Lipid; Microcalorimetry; DCS; Denaturation; Guanidine Hydrochloride; Physics; Fysik; Chemistry; Kemi;

    Sammanfattning : The major part of this thesis deals with the similarities and differences in some biophysical properties of apolipoprotein A-I (apo A-I) and the molecular variant apolipoprotein A-IMilano (apo A-IM), and the influence on lipid binding. A model compound partitioning study has also been performed. LÄS MER

  5. 4. Protein unfolding by interfaces and interactions between polycyclic aromatic hydrocarbons

    Författare :Svetla Chakarova Käck; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; first-principles calculations; PAH; denaturation; protein-interface interactions; van der Waals interactions; lattice models; polycyclic aromatic hydrocarbons; DFT; density functional theory;

    Sammanfattning : In order to theoretically study large and complex systems, a variety of approaches that can be categorized loosely as top-down or bottom-up are followed. While our vision is to bridge the gap between these approaches and use them together in multiscale materials modeling, the present thesis is limited to give examples of each type of approach in the study of soft-matter systems. LÄS MER

  7. 5. Towards First-Principles Understanding of Biomolecular Adsorption

    Författare :Svetla Chakarova Käck; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DFT; phenol; adenine; graphite; biomolecules; van der Waals interactions; denaturation; protein; lattice models; PAH dimers; adsorption;

    Sammanfattning : A fundamental understanding of the interactions of biomolecules, such as proteins and DNA, with surfaces is of immense importance in numerous applications and poses a true challenge for theory. Density functional theory (DFT) is a quantum-mechanical tool well established for its ability to balance large system size with good accuracy in first-principles studies. LÄS MER