Sökning: "defensins"

Visar resultat 1 - 5 av 26 avhandlingar innehållade ordet defensins.

1. 1. Human vaginal epithelial immunity and influences of hormonal contraceptive usage

   Författare :Anna Ildgruben; Nils Lycke; Umeå universitet; []
   Nyckelord :human vaginal epithelium; hormonal contraceptives; epithelial thickness; intraepithelial immune cells; steroid receptors; steroid hormones; defensins; obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : The vagina is the port of entry for sexually transmitted diseases in women. Its epithelium constitutes the luminal border, thus comprising an important defence barrier. LÄS MER

3. 2. Defence capabilities of human intestinal epithelial cells

   Författare :Anna Fahlgren; Sten Hammarström; Marie-Louise Hammarström; Gudmundur Gudmundsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; intestine; mucosa; epithelium; antimicrobial; defensins; glycocalyx; ulcerative colitis; Crohn´s disease; celiac disease; Immunologi; Immunology; Immunologi; immunologi; Immunology;

   Sammanfattning : The epithelial cells lining the intestinal mucosa separate the underlying tissue from components of the intestinal lumen. Innate immunity mediated by intestinal epithelial cells (IECs) provides rapid protective functions against microorganisms. Innate immunity also participates in orchestrating adaptive immunity. LÄS MER

4. 3. Characterization of secreted Giardia intestinalis cysteine proteases

   Författare :Jingyi Liu; Staffan G Svärd; Lars Hellman; Andre Buret; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Giardia intestinalis; ESPs; CPs; apical junction; chemokines; phage display; immunoglobulins; defensins; mucin.; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

   Sammanfattning : Giardia intestinalis, the causative agent of the diarrheal disease giardiasis, is a protozoan parasite that colonizes the upper small intestine of mammals, including humans. It can be divided into eight genotypes or assemblages (A through H) and only assemblage A and B are infective to humans. LÄS MER

5. 4. Mechanisms and Biological Costs of Bacterial Resistance to Antimicrobial Peptides

   Författare :Hava Lofton Tomenius; Dan I Andersson; Ørjan Samuelsen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; antibiotic resistance; fitness cost; Salmonella Typhimurium; Staphylococcus aureus; bile; serum; pH response; growth rate; mice; phoP; pmrB; waaY; LPS; LL-37; defensins; membrane potential; Mikrobiologi; Microbiology;

   Sammanfattning : The global increasing problem of antibiotic resistance necessarily drives the pursuit and discovery of new antimicrobial agents. Antimicrobial peptides (AMPs) initially seemed like promising new drug candidates. Already members of the innate immune system, it was assumed that they would be bioactive and non-toxic. LÄS MER

7. 5. Defensins and cytokines in inflammatory bowel disease

   Författare :Arman Rahman; Mats Andersson; Umeå universitet; []
   Nyckelord :immunologi; Immunology;

   Sammanfattning : Ulcerative colitis (UC) and Crohn’s disease (CD) constitute the two major inflammatory bowel diseases in man. Both are serious chronic illnesses of the intestine with severe debilitating effects. The etiology of the diseases is unknown, but involvement of both adaptive and innate immune reactions seems to be major factors in the pathogenesis. LÄS MER