Sökning: "dGEMRIC"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet dGEMRIC.

  1. 1. Three-dimensional T1 quantification techniques for assessment of cartilage quality using dGEMRIC

    Författare :Carl Siversson; Malmö Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B1; T1; MRI; 3D; correction; dGEMRIC; cartilage; Look-Locker; Variable Flip Angle;

    Sammanfattning : Osteoarthritis (OA) is a common chronic disease and one of the major global causes for functional disabilities. The disease is characterized by loss and degradation of cartilage, commonly affecting the knees and hips. LÄS MER

  2. 2. In vivo Sub-regional dGEMRIC Analysis and Contrast Distribution in Clinical Studies of Human Knee Cartilage

    Författare :Zana Hawezi; Enheten för led- och mjukvävnadsforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MRI; dGEMRIC; sub-regional; knee; cartilage; GAG; meniscus injury; osteoarthritis; exercise.;

    Sammanfattning : Aims: This work was carried out to investigate whether considering cartilage depth in vivo dGEMRIC would provide additional information on the molecular content and changes in normal and diseased cartilage. Methods: Study I was a longitudinal study on 23 healthy volunteers; Study II was a case-control study on 9 sedentary individuals and 8 elite runners. LÄS MER

  3. 3. Contrast-enhanced MRI of human knee cartilage Clinical applications of the novel dGEMRIC technique to study glycosaminoglycan content in articular cartilage

    Författare :Carl Johan Tiderius; Ortopedi - klinisk och molekylär osteoporosforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi; exercise; osteoarthritis; anterior cruciate ligament; glycosaminoglycan; MRI; cartilage; dGEMRIC; knee;

    Sammanfattning : Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a new technique to study cartilage glycosaminoglycan (GAG) content. The negatively charged contrast agent Gd-DTPA2-, injected intravenously, distributes in the cartilage inversely to the likewise negatively charged GAG. LÄS MER

  4. 4. Knee function, Physical Activity and Perceived Health after Meniscectomy in the Middle-aged

    Författare :Ylva Ericsson; Enheten för led- och mjukvävnadsforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; physical activity; dGEMRIC; self efficacy of knee function; functional performance; muscle strength; meniscectomy; middle-aged; health-related quality of life; BMI; functional exercise;

    Sammanfattning : The aim of this thesis was to explore the impact of meniscal injury and meniscectomy on joint and muscle function, physical activity and perceived health in middle-age subjects and to evaluate the effect of a functional exercise program. Male and female post meniscectomy patients participated in Studies I-IV (n=45 in Studies I-III, n=99 in Study IV) and Study IV also included 94 controls. LÄS MER

  5. 5. Ions in models of articular cartilage : The importance of electrostatic interactions for transport and equilibrium distribution

    Författare :Jenny Algotsson; Fysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; articular cartilage; Donnan equilibrium; diffusion; MRI; Monte Carlo simulations; dGEMRIC;

    Sammanfattning : Osteoarthritis (OA) is a degenerative disease that affects articular cartilage, which covers the surfaces of the bones in synovial joints. At later stages the disease can result in major loss of articular cartilage and thus lead to major disability. LÄS MER