Sökning: "cytolethal distending toxin"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden cytolethal distending toxin.

  1. 1. Lipooligosaccharide and Cytolethal distending toxin of Haemophilus ducreyi and antibody responses

    Författare :Annika Lundqvist; Göteborgs universitet; []
    Nyckelord :Haemophilus ducreyi; lipooligosaccharide; cytolethal distending toxin;

    Sammanfattning : The Gram-negative bacterium Haemophilus ducreyi causes chancroid, a sexually transmitted infection characterized by persistent ulcers on genitals. The disease is prevalent in developing countries and facilitates transmission and acquisition of HIV. LÄS MER

  3. 2. Cellular and molecular responses of periodontal connective tissue cells to Actinobacillus actinomycetemcomitans cytolethal distending toxin

    Författare :Georgios N. Belibasakis; Sotirios Kalfas; Ulf H. Lerner; Anders Johansson; Veli-Jukka Uitto; Umeå universitet; []
    Nyckelord :Medical sciences; Actinobacillus actinomycetemcomitans; cytolethal distending toxin; periodontal connective tissue cells; localized aggressive periodontitis; growth arrest; bone resorption; receptor activator of NF-κB ligand; osteoprotegerin; pro-inflammatory cytokines; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; odontologi; Odontology;

    Sammanfattning : Actinobacillus actinomycetemcomitans is present in elevated proportions and numbers in dental bacterial biofilms of patients with localized aggressive periodontitis. This variant of periodontal disease, occurring in adolescents and young adults, is characterized by rapid and severe destruction of the connective tissues and bone supporting the teeth, eventually culminating in tooth loss. LÄS MER

  4. 3. Cellular responses to the DNA damaging cytolethal distending toxin

    Författare :Lina Guerra; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cytolethal distending toxin (CDT) is a genotoxin, which belongs to a group of bacterial protein toxins called cyclomodulins. These are characterized by their interference with the eukaryotic cell cycle. CDT causes DNA damage, which induces cell cycle arrest and apoptosis. LÄS MER

  5. 4. The cytolethal distending toxin of Haemophilus ducreyi. Purification and biological activity

    Författare :Catharina Wising; Göteborgs universitet; []
    Nyckelord :Haemophilus ducreyi; chancroid; STD; CDT; HdCDT;

    Sammanfattning : Haemophilus ducreyi is a Gram-negative bacterium that causes the sexually transmitted disease (STD) chancroid. The disease is endemic in many developing countries, and occurs as restricted outbreaks in the industrialized part of the world. LÄS MER

  7. 5. The cytolethal distending toxin of Haemophilus ducreyi. Prevalence and effects on normal cells

    Författare :Liselott Svensson; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : Haemophilus ducreyi is a fastidious Gram-negative bacterium that causes the sexually transmitted disease chancroid. The disease is endemic in many developing countries and occurs as restricted outbreaks in the industrialised part of the world. LÄS MER