Sökning: "cyclosporine"
Visar resultat 1 - 5 av 40 avhandlingar innehållade ordet cyclosporine.
1. Post-transplantation Hypercholesterolaemia
Sammanfattning : The multidrug regimen, cyclosporine, corticosteroids, and azathioprine, is used in transplantation centres to prevent organ rejection. Several clinical studies have shown that cyclosporine and corticosteroids to cause increases in low density lipoprotein (LDL)-cholesterol, with subsequent development of atherosclerosis. LÄS MER
2. The Hepatobiliary Transport of Rosuvastatin In Vivo
Sammanfattning : In vivo studies of hepatobiliary disposition are challenging. The hepatobiliary system is complex, as its physiological localization, complex cellular structure with numerous transporters and enzymes, and the interindividual variability in protein expression and biliary flow will all affect the in vivo disposition of a drug under investigation. LÄS MER
3. Inhibition of acute allogaft rejection - experimental transplant studies with biological and chemical immunosuppressants
Sammanfattning : In clinical transplantation immunosuppressive agents are used in combination with the objective to achieve additive effects and less toxicity. A large number of novel drugs are candidates for clinical introduction at this time and experiments in animal models have an important role to play. LÄS MER
4. Cerebral Mitochondrial Dysfunction and the Development of Targeted Therapeutics
Sammanfattning : .... LÄS MER
5. Pharmacological interventions against myocardial ischemia and reperfusion injury
Sammanfattning : Background: Ischaemic heart disease is the leading cause of death in the industrialised world. Although the concept of early restoration of coronary blood-flow constitutes an important factor to reduce the injury caused by myocardial ischaemia, reperfusion in itself can aggravate the damage to myocardial tissue, a phenomenon denoted myocardial reperfusion injury. LÄS MER