Sökning: "cryo-TEM"

Visar resultat 11 - 15 av 34 avhandlingar innehållade ordet cryo-TEM.

  1. 11. Controlling DNA compaction and the interaction with model biomembranes

    Författare :Marie-Louise Ainalem; Lunds universitet.; Lund University.; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; model biomembrane; DNA compaction; cryo-TEM; null ellipsometry; dynamic light scattering; toroid; bilayer; neutron reflectivity; dendrimer; PAMAM; DNA; poly amido amine ;

    Sammanfattning : The studies described in this thesis forms part of a larger collaborative project, Neonuclei, with the objective to design a module for packaging the negatively charged DNA into a ”neonucleus” with transcription competence. There are many applications that require control of DNA compaction, i.e. packaging or condensation. LÄS MER

  2. 12. Equilibrium and Kinetic Studies of the Binding of DNA to Cationic Liposomes

    Detta är en avhandling från Physical Chemistry 1, Lund University

    Författare :Paula Barreleiro; Lunds universitet.; Lund University.; [2001]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Small-Angle Neutron Scattering; Fluorescence; Kinetics; Stopped-Flow; Differential Scanning Calorimetry; Titration Calorimetry; Gel-to-Liquid Crystalline Phase Transition; Lamellar phase; Lipolexes; DNA; Liposomes; Cryo-TEM; Physical chemistry; Fysikalisk kemi;

    Sammanfattning : The objective of this work was to study the formation of DNA-cationic vesicle complexes (lipoplexes). These complexes are interesting not only from a fundamental point of view but also as promising candidates for gene therapy. The approach taken was to study first the cationic vesicles by themselves. LÄS MER

  3. 13. Structural Changes in Nonionic Surfactant Systems

    Detta är en avhandling från Lund University (Media-Tryck)

    Författare :Sanja Bulut; Lunds universitet.; Lund University.; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Vesicles; Nonionic Surfactant; Wormlike Micelles; Lamellar Phase; NMR; MRI; SLS; DLS; cryo-fracture-TEM; centrifugation; cryo-TEM;

    Sammanfattning : In this thesis we have studied structural changes of a nonionic surfactant self-assembly, as governed by changes in temperature and concentration. The techniques used in experimental investigations were dynamic and static light scattering, nuclear magnetic resonance and cryo-transmission electron microscopy (using a novel specimen preparation protocol). LÄS MER

  4. 14. Bilayer Discs - Fundamental Investigations and Applications of Nanosized Membrane Models

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Emma Johansson; Uppsala universitet.; [2007]
    Nyckelord :Chemistry; disc; threadlike micelle; liposome; model membrane; drug partitioning; cryo-TEM; Kemi;

    Sammanfattning : The bilayer disc is a flat, lipid aggregate structure in the nanometre regime. It is composed of a bilayer of amphiphilic molecules with micelle-forming amphiphilic molecules supporting the rim, which prevent disc fusion and self-closure. LÄS MER

  5. 15. A Surface Phase Model of the Alveolar Lining: Ultrastructural Analysis and in vivo Applications

    Detta är en avhandling från Marcus Larsson, N. Vallg. 4, 223 62 Lund, Sweden

    Författare :Marcus Larsson; Lunds universitet.; Lund University.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; X-ray diffraction; cryo-TEM; dynamic swelling; ARDS; surface phase; surfactant replacement therapy; cholesterol; minimal surface; pulmonary surfactant; alveolar surface; Physiology; Fysiologi;

    Sammanfattning : In this thesis the relation between lung surfactant structure and functional properties have been studied. Experimental results show that the alveolar surface is formed by a coherent surface phase with a structure equal to tubular myelin. The properties of this phase may explain certain unresolved issues in lung physiology, e.g. LÄS MER