Sökning: "cotranscriptional assembly"

Hittade 3 avhandlingar innehållade orden cotranscriptional assembly.

  1. 1. Characterization of RNA exosome in Insect Cells : Role in mRNA Surveillance

    Författare :Viktoria Hessle; Neus Visa; Maria Carmo-Fonseca; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cell nucleus; nuclear bodies; mRNA surveillance; cotranscriptional assembly; Rrp6; Rrp4; mRNP; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Sammanfattning : The exosome, an evolutionarily conserved protein complex with exoribonucleolytic activity, is one of the key players in mRNA quality control. Little is known about the functions of the exosome in metazoans. We have studied the role of the exosome in nuclear mRNA surveillance using Chironomus tentans and Drosophila melanogaster as model systems. LÄS MER

  3. 2. Assembly and transport of messenger and ribosomal RNP particles in the dipteran Chironomus tentans

    Författare :Teresa Soop; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Gene expression in eukaryotic organisms commences with the synthesis of a precursor RNA, which has to be extensively processed to yield a mature RNA molecule. In addition to processing, the RNA molecule needs to associate with a proper set of proteins. LÄS MER

  4. 3. Transcription and transport of a messenger RNP particle : novel regulatory mechanisms

    Författare :Karin Kylberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In all living cells gene expression is a central process that involves several steps, including transcription, processing, transport and translation. A fine-tuning of these events is a pre-requisite for proper cellular function. LÄS MER