Sökning: "connective tissue growth factor"

Visar resultat 1 - 5 av 27 avhandlingar innehållade orden connective tissue growth factor.

  1. 1. Connective tissue contraction in wound healing : An experimental study in vivo and in vitro

    Författare :M. Reza Ghassemifar; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Contraction of connective tissue is an important part of tissue repair that reduces the wound space and helps to decrease the formation of scar tissue, both of which are needed to restore tissue integrity. In the present study, certain cellular mechanisms that are active during connective tissue contraction were assessed and the influence of transforming growth factor-. LÄS MER

  3. 2. Stimulation of wound healing in connective tissue : An experimental study using the perforated rat mesentery

    Författare :Per Malcherek; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Different aspects of wound healing in connective tissue were studied in the perloratedrat- mesentery model after mast cell activation and treatment with epidermal growth factor (EGF). This wound model is considered to reflect pure connective tissue repair. LÄS MER

  4. 3. Integrin αVβ3-Directed Contraction by Connective Tissue Cells : Role in Control of Interstitial Fluid Pressure and Modulation by Bacterial Proteins

    Författare :Åsa Lidén; Kristofer Rubin; Karl-Eric Magnusson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; interstitial fluid pressure; collagen gel contraction; integrin αVβ3; septic shock; fibronectin; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : This thesis aimed at studying mechanisms involved in control of tissue fluid homeostasis during inflammation.The interstitial fluid pressure (PIF) is of importance for control of tissue fluid balance. A lowering of PIF in vivo will result in a transport of fluid from the circulation into the tissue, leading to edema. LÄS MER

  5. 4. On vascular endothelial growth factor B and platelet-derived growth factor C : two members of the VEGF/PDGF family of growth factors

    Författare :Karin Aase; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Vascular endothelial growth factors (VEGFs), platelet-derived growth factors (PDGFs) and their receptors are important for normal development. They have also been implicated in many pathological conditions. VEGFs have been shown to play an important role in the development of both blood and lymphatic vessels. LÄS MER

  7. 5. Novel biomarkers in regulating human dense connective tissue repair

    Författare :Junyu Chen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Painful and degenerative disorders of the musculoskeletal system pose a tremendous burden on the healthcare system. One main reason is the limited knowledge of the underlying key factors and pathways responsible for the suboptimal and often varying healing outcomes of dense connective tissues (CTs), such as tendons, ligaments and knee meniscus, which have vital supportive, protective and force transmitting roles in the human body. LÄS MER