Sökning: "connective tissue growth factor"
Visar resultat 1 - 5 av 27 avhandlingar innehållade orden connective tissue growth factor.
1. Connective tissue contraction in wound healing : An experimental study in vivo and in vitro
Sammanfattning : Contraction of connective tissue is an important part of tissue repair that reduces the wound space and helps to decrease the formation of scar tissue, both of which are needed to restore tissue integrity. In the present study, certain cellular mechanisms that are active during connective tissue contraction were assessed and the influence of transforming growth factor-. LÄS MER
2. Stimulation of wound healing in connective tissue : An experimental study using the perforated rat mesentery
Sammanfattning : Different aspects of wound healing in connective tissue were studied in the perloratedrat- mesentery model after mast cell activation and treatment with epidermal growth factor (EGF). This wound model is considered to reflect pure connective tissue repair. LÄS MER
3. Integrin αVβ3-Directed Contraction by Connective Tissue Cells : Role in Control of Interstitial Fluid Pressure and Modulation by Bacterial Proteins
Sammanfattning : This thesis aimed at studying mechanisms involved in control of tissue fluid homeostasis during inflammation.The interstitial fluid pressure (PIF) is of importance for control of tissue fluid balance. A lowering of PIF in vivo will result in a transport of fluid from the circulation into the tissue, leading to edema. LÄS MER
4. On vascular endothelial growth factor B and platelet-derived growth factor C : two members of the VEGF/PDGF family of growth factors
Sammanfattning : Vascular endothelial growth factors (VEGFs), platelet-derived growth factors (PDGFs) and their receptors are important for normal development. They have also been implicated in many pathological conditions. VEGFs have been shown to play an important role in the development of both blood and lymphatic vessels. LÄS MER
5. Novel biomarkers in regulating human dense connective tissue repair
Sammanfattning : Painful and degenerative disorders of the musculoskeletal system pose a tremendous burden on the healthcare system. One main reason is the limited knowledge of the underlying key factors and pathways responsible for the suboptimal and often varying healing outcomes of dense connective tissues (CTs), such as tendons, ligaments and knee meniscus, which have vital supportive, protective and force transmitting roles in the human body. LÄS MER