Sökning: "conformational studies"

Visar resultat 1 - 5 av 258 avhandlingar innehållade orden conformational studies.

  1. 1. Conformational Stability!? : Synthesis and Conformational Studies of Unnatural Backbone Modified Peptides

    Författare :Anna S. Norgren; Per I. Arvidsson; Norbert Sewald; Uppsala universitet; []
    Nyckelord :Organic chemistry; Conformational investigations; β-peptides; glycosylation; biomolecular recognition; cyclic β³-peptides; cyclic mixed α β²-peptides; β-peptoids; Organisk kemi;

    Sammanfattning : The beauty of the wide functionality of proteins and peptides in Nature is determined by their ability to adopt three-dimensional structures. This thesis describes artificial molecules developed to mimic secondary structures similar to those found crucial for biological activities. LÄS MER

  3. 2. Infrared studies : Method development and binding of ligands to pyruvate kinase

    Författare :Saroj Kumar; Andreas Barth; Christopher Wharton; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Biophysics; biofysik;

    Sammanfattning : Infrared spectroscopy is a valuable technique for the study of ligand induce change in biomolecules. Our development of a dialysis accessory to attenuated total reflection infrared spectroscopy makes this technique more universal for ligand binding studies. LÄS MER

  4. 3. Asymmetric Catalysis : Ligand Design and Conformational Studies

    Författare :Kristina Hallman; KTH; []
    Nyckelord :asymmetric catalysis; chiral ligand; oxazolines; conformational study; allylic substitution; polymer-bound ligands; dendritic ligands; crown ether; oxidations; palladacycle;

    Sammanfattning : This thesis deals with the design of ligands for efficientasymmetric catalysis and studies of the conformation of theligands in the catalytically active complexes. All ligandsdeveloped contain chiral oxazoline heterocycles. LÄS MER

  5. 4. Exploring the structure of oligo- and polysaccharides : Synthesis and NMR spectroscopy studies

    Författare :Hanna Jonsson; Göran Widmalm; Antonio Molinaro; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Carbohydrates; NMR spectroscopy; synthesis; lipopolysaccharides; conformational studies; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : A deeper understanding of the diversity of carbohydrates and the many applications of oligo- and polysaccharides found in nature are of high interest. Many of the processes involving carbohydrates affect our everyday life. This thesis is based on six papers all contributing to an extended perspective of carbohydrate property and functionality. LÄS MER

  7. 5. Structural and Conformational Studies of Oligo- and Polysaccharides

    Författare :Mona Zaccheus; Göran Widmalm; Christina De Castro; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; structural analysis; conformational analysis; carbohydrates; polysaccharides; organisk kemi; Organic Chemistry;

    Sammanfattning : The focus of this thesis is to examine the structural properties of polysaccharides produced by bacteria, as well as the dynamic and conformational behavior of a synthetically derived oligosaccharide.The primary structures of the O-polysaccharide repeating units of four different Escherichia coli (E. LÄS MER