Sökning: "colonic mucus thickness"

Hittade 4 avhandlingar innehållade orden colonic mucus thickness.

  1. 1. Microcirculation, Mucus and Microbiota in Inflammatory Bowel Disease

    Författare :Olof Schreiber; Lena Holm; Mia Phillipson; Henrik Sjövall; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammatory bowel diseases; experimental colitis; DSS; TNBS; colonic mucosal blood flow; laser-doppler flowmetry; colonic mucus thickness; MUC2; colonic mucosal barrier function; iNOS; eNOS; probiotics; Lactobacilli; Lactobacillus reuteri; colonic microbiota; T-RFLP; bacterial translocation; intravital microscopy; P-selectin; leukocyte recruitment; platelet recruitment; Physiology; Fysiologi; Physiology; Fysiologi;

    Sammanfattning : Inflammatory bowel diseases, (IBD), are a group of chronic disorders of the gastro-intestinal tract, and include Crohn’s disease (CD) and Ulcerative Colitis (UC). The pathogenesis is not known, but involves at least in part a loss of tolerance towards the commensal colonic microbiota. LÄS MER

  3. 2. Citrobacter rodentium and Escherichia coli interactions with mucus producing colonic epithelical cells

    Författare :Sinan Sharba; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; A E pathogens; cytokines; epithelium; mitochondria; mucus;

    Sammanfattning : The epithelial cells together with the mucus layer protect the host from noxious luminal substances and pathogenic invasion. Pathogens have evolved numerous strategies to circumvent these barriers and mount infection. C. rodentium is a murine model for the attaching and effacing intestinal E. LÄS MER

  4. 3. Mucus and mucins during gastrointestinal infections

    Författare :Nazanin Navabi; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucin; gastrointestinal cell lines; mucus layer; secreted mucin; cell surface mucin; H. pylori; C. rodentium; ETEC; mucin secretion; goblet cells;

    Sammanfattning : The gastrointestinal tract is protected by a continuously secreted mucus layer formed by mucin glycoproteins. The mucus layer and mucins change dynamically during infection. The main focus of this thesis was to investigate the changes in mucin and the mucus layer in the gastrointestinal tract during infection with the gastrointestinal pathogens C. LÄS MER

  5. 4. Diet and inflammation : the role of nitrate and conjugated linoleic acid

    Författare :Cecilia Jädert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A diet rich in vegetables and unsaturated fatty acids is associated with a lower risk of major diseases including cardiovascular disease, type 2 diabetes and chronic inflammation. Yet, despite extensive research, the active component(s) responsible for these effects has not been pinpointed and studies with single nutrients have been largely unsuccessful. LÄS MER