Sökning: "collagen VI"

Visar resultat 1 - 5 av 62 avhandlingar innehållade orden collagen VI.

  1. 1. Collagen VI - Molecular Assembly and Interactions

    Författare :Charlotte Wiberg; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical biology; extracellular matrix; glycosaminoglycan; proteoglycan; collagen; biglycan; decorin; Klinisk biologi;

    Sammanfattning : The extracellular matrix plays an integral role in tissue remodeling and development and it defines the different mechanical properties of a variety of connective tissues. Its complexity in composition and the details in organization has only been partly elucidated. LÄS MER

  3. 2. The role of leucine-rich repeat glycoproteins/proteoglycans in the assembly of collagen matrices

    Författare :Liz Svensson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reumatologi; muskelsystem; Skelett; decorin; Collagen; fibromodulin; extracellular matrix; lumican; collagen fibrillogenesis; Skeleton; rheumatology locomotion; muscle system; Biochemistry; Biokemi; Metabolism;

    Sammanfattning : The properties of different connective tissues depend on the synthesis and assembly of macromolecular structures composed of collagen and other extracellular matrix components. Mechanisms modulating these events play important roles in the formation of a functional tissue. LÄS MER

  4. 3. Host Defense Properties of Collagen VI. A novel concept in connective tissue innate immunity

    Författare :Suado M Abdillahi; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Innate Immunity; Antimicrobial peptides; Collagen VI; Chronic obstructive pulmonary disease COPD ;

    Sammanfattning : Rapid and powerful host defense mechanisms are essential in order to overcome harmful actions of pathogenic bacteria. Antimicrobial peptides (AMPs) and proteins are vital effector molecules of the fast-acting innate immune system and exist virtually in all living organisms. LÄS MER

  5. 4. Extracellular Matrix Remodelling-Proteoglycan and collagen turnover in arthritis

    Författare :Anette Bjärdahlen; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Arthritis; collagen; cartilage; myofibroblasts; pannus; proteoglycan; Skeleton; muscle system; rheumatology locomotion; reumatologi; Skelett; muskelsystem;

    Sammanfattning : Rheumatoid arthritis is a chronic, inflammatory and systemic disease characterised by joint destruction and pannus formation. To enlarge the understanding how pannus and granulation tissue are formed two animal models were used; one using cartilage wrapped in cotton and implanted into a rat air pouch (AP) and one where mBSA induced arthritis (AIA) was performed. LÄS MER

  7. 5. The collagen fibrillar network: Sequential degradation of its constituents by tissue metalloproteinases

    Författare :Terrence Heathfield; Enheten för led- och mjukvävnadsforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolism; Metabolism; Biochemistry; collagen; fibromodulin; cartilage; osteoarthritis; Biokemi;

    Sammanfattning : The cartilage matrix is made up of a fibrillar meshwork comprising type II collagen and other associated proteins. One main function of this network is to retain the large aggregating proteoglycan, aggrecan, a vital component in the regulation of fluid flux in cartilage. LÄS MER