Sökning: "coculture"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet coculture.

1. 1. Interactions between Malignant Keratinocytes and Fibroblasts : Studies in Head and Neck Squamous Cell Carcinoma

   Författare :Malin Hakelius; Daniel Nowinski; Bengt Gerdin; Kristofer Rubin; Avni Abdiu; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coculture; extracellular matrix; interleukin-1 alpha; tumor stroma; differential gene regulation; innate response; Plastic Surgery; Plastikkirurgi;

   Sammanfattning : Carcinoma growth requires a supportive tumor stroma. The concept of reciprocal interactions between tumor and stromal cells has become widely acknowledged and the connective tissue activation seen in the malignant process has been likened to that of a healing wound. LÄS MER

3. 2. Regulation of fibroblast activity by keratinocytes, TGF-β and IL-1α : studies in two- and three dimensional in vitro models

   Författare :Anita Koskela von Sydow; Mikael Ivarsson; Torbjörn Bengtsson; Hans Törmä; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fibroblast; Keratinocyte; TGF-β; IL-1α; coculture; fibrosis CTGF CNN 2; dermal; organotypic culture;

   Sammanfattning : Dysregulated wound healing is commonly associated with excessive fibrosis. Connective tissue growth factor (CTGF/CCN2) is characteristically overexpressed in fibrotic diseases and stimulated by transforming growth factor-β (TGF-β) in dermal fibroblasts. Reepithelialisation and epidermal wound coverage counteract excessive scar formation. LÄS MER

4. 3. Amoebae as Hosts and Vectors for Spread of Campylobacter jejuni

   Författare :Jenny Olofsson; Patrik Ellström; Björn Olsen; Diana Axelsson-Olsson; Hans Lindmark; Uppsala universitet; []
   Nyckelord :Amoebae-Bacteria interactions; Campylobacter jejuni; epidemiology; environmental stress; low pH; Acanthamoeba; coculture; intracellular trafficking; bacterial survival; beverages; ACC-method; enrichment; genetic stability; Trojan horse; reservoir; host; vector; Infektionssjukdomar; Infectious Diseases;

   Sammanfattning : Campylobacter jejuni is the leading bacterial cause of gastrointestinal diarrheal disease in humans worldwide. This zoonotic pathogen has a complex epidemiology due to its presence in many different host organisms. LÄS MER

5. 4. Function and Regulation of B-cell Subsets in Experimental Autoimmune Arthritis

   Författare :Anna-Karin E. Palm; Sandra Kleinau; Susanna Cardell; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; B cells; marginal zone; autoimmune arthritis; spleen; lymph node; antigen presentation; Fc gamma receptor IIb; complement receptors 1 and 2; mast cells; Biologi med inriktning mot molekylär immunologi; Biology with specialization in Molecular Immunology;

   Sammanfattning : B lymphocytes play a significant role in autoimmune arthritis, with their function stretching beyond autoantibody production to cytokine secretion and presentation of autoantigen. However, the involvement and activation of different B-cell subset in the autoimmune response is not fully clear. LÄS MER

7. 5. Exploring the interaction between the human microbiota and infections

   Författare :Liqin Cheng; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The microbiota is a living ecosystem that is influenced by a variety of host and environmental factors. Distinct microbiota colonizes various body sites, such as the gastrointestinal system and vaginal tract, corresponding to the unique microenvironment. A healthy gut microbiota contains a stable, balanced, and highly diverse reservoir of microbes. LÄS MER