Sökning: "clonidine"

Visar resultat 1 - 5 av 19 avhandlingar innehållade ordet clonidine.

1. 1. Neonatal Exposure to Anaesthesia and Adjuvants : Acute Effects on Cerebral Apoptosis and Neuroproteins, and Late  Behavioural Aberrations in Mice

   Författare :Emma Pontén; Anders Fredriksson; Torsten Gordh; Steen Henneberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anaesthesia; neonatal; apoptosis; bahaviour; clonidine; ketamine; propofol; theophyllamine; Medicin; Medicine;

   Sammanfattning : During a finite developmental phase – the brain growth spurt – the brain grows and matures at an accelerated rate. During this period the brain is more sensitive to harmful substances such as ethanol and environmental toxins than before or after. LÄS MER

3. 2. Cerebral circulation and the sympathetic nervous system in patients with traumatic brain injury or subarachnoid hemorrhage

   Författare :Silvana Naredi; Göteborgs universitet; []
   Nyckelord :traumatic brain injury; brain edema; microcirculation; intracranial pressure; epo-prostenol; norepinephrine; subarachnoid hemorrhage; sympathetic nervous system; clonidine;

   Sammanfattning : Maintenance of adequate cerebral microcirculation is necessary to avoid cerebral ischemia after severe traumatic brain injury and non-traumatic subarachnoid hemorrhage. After severe traumatic brain injury the blood-brain-barrier is disrupted and transcapillary leakage will contribute to the development of vasogenic brain edema. LÄS MER

4. 3. Conctraction-mediating receptors in human peripheral vessels with special reference to veins and lymphatics

   Författare :Trygve Sjöberg; Thoraxkirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human; arteries; veins; lymphatis; contraction; in vitro; in vivo; adrenergic receptors; noradrenaline; cirazoline; phenylephrine; clonidine; calcium antagonists; nifedipine; diltiazem; prostaglandins; thromboxane A2; U-46619; BM-13.505; indomethacin;

   Sammanfattning : By means of a myograph, postjunctional alpha-adrenoceptors were characterized in human superficial epigastric arteries and veins obtained from health subjects. The rank order of potency of subtype selective agonists could not be used for receptor characterization in these vessels, whereas antagonists gave distinct results. LÄS MER

5. 4. Clonidine in paediatric anaesthesia : pharmacokinetic and pharmacodynamic aspects

   Författare :Henrik T G Bergendahl; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Alpha-2 adreoceptor agonists; anaesthesia; analgesia; bioavailability; clonidine; confusion; dose response; epidural; haemodynamics; intubation tracheal; midazolam; neuropeptide Y; paediatric; pharmacokinetic; postoperative; postoperative vomiting; premedication; sedation; shivering; variability.;

   Sammanfattning : Clonidine is a mixed alpha-2/alpha-1 adrenoceptor agonist. It reduces sympathetic and increases parasympathetic tone which results in a lowering of the baseline blood pressure and heart rate. LÄS MER

7. 5. Perioperative effects of systemic or spinal clonidine as adjuvant during spinal anaesthesia

   Författare :Igor Dobrydnjov; Torsten Gordh Jr.; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Aim of study: To evaluate the effects of different doses of clonidine administered systemically or spinally in combination with local anaesthetics on sensory and motor block intraoperatively, on pain relief postoperatively, and on the incidence of postoperative alcohol withdrawal syndrome (AWS) in alcohol abusers.Patients and methods: A total 285 patients were included in five studies. LÄS MER