Sökning: "clinical relevance"
Visar resultat 1 - 5 av 438 avhandlingar innehållade orden clinical relevance.
1. Gastroenteropancreatic Neuroendocrine Neoplasms Grade 3 : Biological and Clinical Aspects
Sammanfattning : The aim of this thesis was to investigate biological and clinical aspects of G3 gastroenteropancreatic neuroendocrine neoplasms (G3 GEP-NENs).In our first study, the expression of the tumor suppressor p53 was investigated. In a cohort of G3 GEP-NENs we found the expression of p53 protein to be present in 39% of 124 cases. LÄS MER
2. Spatial immune analyses in clinical cancer tissue
Sammanfattning : Cancer is a leading cause of premature death and lung cancer is the deadliest cancer type, with non-small cell lung cancer (NSCLC) representing 85% of lung cancer cases. Despite promising development in cancer treatment in recent decades, overall prognosis is poor. LÄS MER
3. Clinical Pharmacogenetics of Olanzapine : with Focus on FMO Gene Polymorphisms
Sammanfattning : Pharmacogenetics is the study of variability in drug response attributed to genetic variation. Olanzapine (OLA) is a widely used antipsychotic drug for schizophrenia treatment. The pharmacokinetics of OLA display large inter-individual variation leading to multiple-fold differences in drug exposure between patients at a given dose. LÄS MER
4. SCHIZOPHRENIA IN A LONGITUDINAL PERSPECTIVE clinical and neurocognitive aspects
Sammanfattning : Objective: To explore the long-term course and to study factors of potential relevance for the treatment and rehabilitation process of patients with schizophrenia and schizophrenia-like disorders. Specific issues concerned cognitive reduction, tardive dyskinesia (TD), prolactin-induced side effects, remission and lack of insight. LÄS MER
5. Clinical relevance of high-sensitive Troponin T in cardiovascular disease
Sammanfattning : Background and aims: Troponin T (hs-cTnT) is a cardiac damage marker used in the diagnosis of non-ST segment elevation myocardial infarction (NSTEMI) and for prognostic assessment. Clinical decision-making should ideally be based on evidence. LÄS MER