Sökning: "cleavage"

Visar resultat 1 - 5 av 526 avhandlingar innehållade ordet cleavage.

  1. 1. Haematopoietic Serine Proteases : A Cleavage Specificity Analysis

    Författare :Michael Thorpe; Lars Hellman; Urban Gullberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cell; cleavage specificity; phage display; chymase; serine protease; granzyme; fish protease;

    Sammanfattning : Mast cells are innate immune cells, historically involved in allergy responses involving IgE. Through this, they have earned a reputation as a fairly detrimental cell type. Their beneficial roles remain somewhat enigmatic although they clearly have the ability to modulate the immune system. LÄS MER

  3. 2. Computational Prediction Models for Proteolytic Cleavage and Epitope Identification

    Författare :Liwen You; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; medical informatics; biomathematics biometrics; Bioinformatics; SVM; sequence analysis; rule extraction; protease-peptide interaction; OSRE; MHC; immunology; HIV; hierarchical method; HCV; Gaussian process; false positive; epitope; cleavage specificity; cleavage prediction; binding affinity; caspase; Bioinformatik; medicinsk informatik; biomatematik; Computer science; numerical analysis; systems; control; Datalogi; numerisk analys; system; kontroll; Binding affinity; Bioinformatics;

    Sammanfattning : The biological functions of proteins depend on their physical interactions with other molecules, such as proteins and peptides. Therefore, modeling the protein-ligand interactions is important for understanding protein functions in different biological processes. LÄS MER

  4. 3. Cleavage Specificity of Mast Cell Chymases

    Författare :Mattias K. Andersson; Lars Hellman; Gunnar Pejler; Per Venge; Uppsala universitet; []
    Nyckelord :Biology; Immunology; Mast cell; Serine protease; Chymase; Cleavage specificity; Phage display; Biologi;

    Sammanfattning : Mast cells (MC) are potent inflammatory cells that are known primarily for their prominent role in IgE mediated allergies. However, they also provide beneficial functions to the host, e.g. in bacterial and parasitic defence. LÄS MER

  5. 4. Probabilistic and micromechanical modelling of cleavage fracture

    Författare :Martin Kroon; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; cleavage fracture; probabilistic; micromechanical; TECHNOLOGY; TEKNIKVETENSKAP; Maskinteknik;

    Sammanfattning : .... LÄS MER

  7. 5. Micromechanical modeling of cleavage fracture in polycrystalline materials

    Författare :Mateusz Stec; Jonas Faleskog; Andre Pineau; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; cleavage fracture; probabilistic modeling; brittle to ductile transition; cohesive zone; visco-plastic material; Engineering mechanics; Teknisk mekanik; Other technology; Övriga teknikvetenskaper;

    Sammanfattning : Cleavage fracture in ferritic steels can be defined as a sequence of few critical steps. At first nucleation of a microcrack takes place, often in a hard inclusion. This microcrack then propagates into the surrounding matrix material. The last obstacle before failure is the encounter of grain boundaries. LÄS MER