Sökning: "citrate synthase"
Visar resultat 6 - 10 av 22 avhandlingar innehållade orden citrate synthase.
6. Role of Cell-cell Interactions and Palmitate on β-cells Function
Sammanfattning : The islets of Langerhans secrets insulin in response to fluctuations of blood glucose level and efficient secretion requires extensive intra-islet communication. Secretory failure from islets is one of the hallmark in progression of type 2 diabetes. LÄS MER
7. Studies on exercise and glycogen re-synthesis in skeletal muscles of pigs with the PRKAG3 mutation
Sammanfattning : AMP-activated protein kinase (AMPK) plays an important role in the regulation of glucose and lipid metabolism in skeletal muscle. Many pigs of Hampshire origin have a naturally occurring mutation situated in the PRKAG3 gene which encodes a muscle-specific isoform of the AMPK γ3-subunit. LÄS MER
8. The conserved methionines in the chloroplast small heat shock protein - Role in chaperone-substrate interactions and effects of methionine sulfoxidation on chaperone activity
Sammanfattning : The chloroplast-localized small heat shock protein (sHsp) Hsp21 belongs to the family of alpha-crystallin like sHsps which form large oligomeric structures and protect partly unfolded aggregation-prone proteins against aggregation. The main focus for this thesis has been on the highly conserved methionines in Hsp21. LÄS MER
9. Physical exercise and electrical stimulation in the management of metabolic, cardiovascular and skeletal-muscle alterations in people with tetraplegia
Sammanfattning : Interruption of the spinal cord at the cervical level leads to permanent extensive motor paralysis, serious autonomic regulation deficits and profound short term and long term metabolic disorders. The defects play a decisive role for the tetraplegic individuals future function and health. LÄS MER
10. Exploring small heat shock protein chaperones by crosslinking mass spectrometry
Sammanfattning : Together with other molecular chaperones, small heat shock proteins are key components of the protein quality control system, which is comprised of several hundred proteins and acts to maintain proteome homeostasis in the cell. Small heat shock proteins bind unfolding proteins at an early stage, to prevent these from further unfolding and aggregating. LÄS MER